Langner H J, Sinell H J
Vet Med Nauki. 1976;13(6):36-43.
Experimentally were demonstrated the difficulties overcome and the possibilities of producing a Staphylococcus-enterotoxin D antiserum of a 1:80 titer. The product was shown to be suitable for work as well as for further studies. Given are the schemes of immunizing a rabbit serving as a serum producer and those for purifying the antiserum (eliminating heterologous antibodies), its titration with a microimmunodiffusion test, etc. In this connection some problems are referred to concerning the production of the amounts necessary of enterotoxin D, its purification and toxicity for test animals, etc., that are successfully solved by the authors.
通过实验证明了克服困难以及生产效价为1:80的葡萄球菌肠毒素D抗血清的可能性。结果表明，该产品适用于相关工作以及进一步研究。文中给出了作为血清产生者的兔子免疫方案以及抗血清纯化方案（去除异源抗体）、用微量免疫扩散试验进行滴定等。关于肠毒素D所需量的生产、其纯化以及对实验动物的毒性等问题也有提及，作者已成功解决了这些问题。
