Boehme C, Soto L, Rodríguez G, Serra J, Illesca V, Reydet P
Unidad de Microbiología, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.
Rev Med Chil. 1993 Jun;121(6):633-8.
The aim of this work was to study the clinical, epidemiological and laboratory features of 90 children, hospitalized between 1988 and 1991 with the diagnosis of acute bacterial meningitis in a region with a high proportion of aboriginal population. Twenty six percent of studied patients were of mapuche origin. The causative organism was identified in 82% of cases (H influenzae in 38% of cases, S pneumoniae in 29% and N meningitidis in 10%). H influenzae was resistant to ampicillin in 16% of cases and resistant to chloramphenicol in 4%. This agent was identified in 52% of patients of mapuche origin compared with 33% of non mapuche patients. Seventy three percent of children were less than 2 years old. Thirty seven percent of children had complications during hospitalization, 12 children died (13.3%) and 38% of children had neurological sequelae at the moment of discharge.
这项工作的目的是研究1988年至1991年间在一个原住民人口比例很高的地区住院的90例诊断为急性细菌性脑膜炎的儿童的临床、流行病学和实验室特征。26%的研究患者为马普切族裔。82%的病例中确定了病原体(38%的病例为流感嗜血杆菌,29%为肺炎链球菌,10%为脑膜炎奈瑟菌)。16%的病例中流感嗜血杆菌对氨苄西林耐药,4%对氯霉素耐药。该病原体在52%的马普切族裔患者中被发现,而非马普切族患者中为33%。73%的儿童年龄小于2岁。37%的儿童在住院期间出现并发症,12名儿童死亡(13.3%),38%的儿童在出院时存在神经后遗症。