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曼氏血吸虫病初期非显性临床症状的特征

Characterization of the non-apparent clinical form in the initial phase of schistosomiasis mansoni.

作者信息

Rocha M O, Pedroso E R, Neves J, Rocha R S, Greco D B, Lambertucci J R, Rocha R L, Katz N

机构信息

Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 1993 May-Jun;35(3):247-51. doi: 10.1590/s0036-46651993000300005.

DOI:10.1590/s0036-46651993000300005
PMID:8278754
Abstract

In this paper the history of 115 recruits that had bathed simultaneously in streams contaminated with Schistosoma mansoni, during military maneuvers, is reported. Thirty four of the infected patients presented the initial phase of the infection diagnosed through epidemiologic, clinical and laboratory parameters. Three out of the 34 patients did not reveal the clinical picture of the infection, thus being considered representatives of the non-apparent form of the disease. Differences between the intensity of blood eosinophilia, the area of immediate cutaneous reaction and the number of Schistosoma eggs eliminated in the stools proved not to be statistically significant (p > 0.05) when the non-apparent and acute cases of schistosomiasis were compared. These cases actually may be considered evidences of the non-apparent form hitherto merely taken for granted in the literature.

摘要

本文报告了115名新兵的病史,他们在军事演习期间同时在受曼氏血吸虫污染的溪流中沐浴。34名受感染患者通过流行病学、临床和实验室参数被诊断为处于感染初期。34名患者中有3名未表现出感染的临床症状,因此被视为该疾病非显性形式的代表。当比较血吸虫病的非显性和急性病例时,血液嗜酸性粒细胞增多的强度、即刻皮肤反应面积和粪便中排出的血吸虫卵数量之间的差异没有统计学意义(p>0.05)。这些病例实际上可被视为迄今在文献中仅被视为理所当然的非显性形式的证据。

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Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees.辐射减毒疫苗诱导黑猩猩产生的针对血吸虫的细胞免疫和体液免疫反应及保护作用。
Infect Immun. 2001 Sep;69(9):5352-62. doi: 10.1128/IAI.69.9.5352-5362.2001.