Le Pailleur C, Lafont H, Meilhac B, Fleury G, Vacheron A, Mattéo J D
Arch Mal Coeur Vaiss. 1976 Mar;69(3):239-46.
The 19 coronary patients studied were found to have a "normalised" rigidity k = dp/(dVP) identical to that of normal subjects, and a lowered instantaneous end-diast-lic compliance (dV/dP)TD. The increase in end-diastolic pressure is due to a small increase in end-diastolic volume, and brings about Starling's phenomenon to compensate for a diminution in contractility. The maximimum speed of shortening of the myocardium (VCFmax) shows up the baseline contractility, and appears to be more sensitive than the mean speed of myocardial shortening (VCF) and the ejection fraction.
研究的19名冠心病患者被发现具有与正常受试者相同的“标准化”刚度k = dp/(dVP),且舒张末期瞬时顺应性(dV/dP)TD降低。舒张末期压力的升高是由于舒张末期容积的小幅增加,并引发了斯塔林现象以补偿收缩力的降低。心肌缩短的最大速度(VCFmax)显示了基线收缩力,并且似乎比心肌缩短的平均速度(VCF)和射血分数更敏感。