Yasujima H, Komatsu M, Sakurai T, Kodama S
Department of Pediatrics, Himeji Red Cross Hospital, Hyogo.
No To Hattatsu. 1994 Jan;26(1):32-7.
Fourteen children meeting the NIH consensus diagnostic criteria for NF 1 were evaluated at the Department of Pediatrics, Himeji Red Cross Hospital. MRI and EEG were examined in all patients, respectively. Four of 14 patients had a history of epilepsy, two had suffered West syndrome, one had complex partial seizures and one had secondary generalized partial epilepsy. Seven (50%) of 14 patients showed abnormal MRI; three (75%) of 4 patients with epilepsy and four (40%) of 10 patients with epilepsy showed low intensity on T1 weighted images and hyperintensity on T2 weighted images in the globus pallidus and brainstem. These results suggest that children with NF 1 have a spectrum of MRI abnormalities, irrespective of existence of epilepsy.
十四名符合美国国立卫生研究院（NIH）关于1型神经纤维瘤病（NF 1）共识诊断标准的儿童在姬路红十字医院儿科接受了评估。所有患者均分别接受了磁共振成像（MRI）和脑电图（EEG）检查。14名患者中有4名有癫痫病史，2名曾患韦斯特综合征，1名有复杂部分性发作，1名有继发性全身性部分性癫痫。14名患者中有7名（50%）MRI显示异常；4名癫痫患者中有3名（75%）以及10名非癫痫患者中有4名（40%）在苍白球和脑干的T1加权图像上显示低信号，在T2加权图像上显示高信号。这些结果表明，无论是否存在癫痫，NF 1患儿都存在一系列MRI异常。
