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唇腭裂三个月大儿童的蝶枕软骨结合:一项影像学研究。

Spheno-occipital synchondrosis in three-month-old children with clefts of the lip and palate: a radiographic study.

作者信息

Mølsted K, Kjaer I, Dahl E

机构信息

Department of Orthodontics, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark.

出版信息

Cleft Palate Craniofac J. 1993 Nov;30(6):569-73. doi: 10.1597/1545-1569_1993_030_0569_sositm_2.3.co_2.

DOI:10.1597/1545-1569_1993_030_0569_sositm_2.3.co_2
PMID:8280735
Abstract

The literature has been focused on differences in craniofacial form and dimension in cleft lip and palate patients. No attention has been given to possible alterations in the spheno-occipital synchondrosis although the synchondrosis is regarded as an important maturity and growth center. The purpose of the present investigation was to examine if the spheno-occipital synchondrosis in children born with major complete clefts differs on lateral radiographs from that of children born with minor incomplete clefts. Fifty-seven three-month-old children with complete clefts of the lip, alveolus and palate and 42 three-month-old children with minor incomplete clefts of the lip were included in the study. The results of the comparison showed that children with complete major clefts had a broader spheno-occipital synchondrosis compared to children with a minor incomplete cleft of the lip, and that the distance from the superior part of the synchondrosis to the sella point was shorter in children with complete clefts. These findings could be related to a defect or a delay in maturity in the early development of the cartilaginous cranial base in children with major clefts.

摘要

文献一直聚焦于唇腭裂患者颅面形态和尺寸的差异。尽管蝶枕软骨结合被视为一个重要的成熟和生长中心,但尚未有人关注其可能存在的改变。本研究的目的是检查患有主要完全性腭裂的儿童与患有轻微不完全性腭裂的儿童相比,其蝶枕软骨结合在侧位X线片上是否存在差异。本研究纳入了57名3个月大的唇、牙槽突和腭裂完全性腭裂患儿以及42名3个月大的唇轻微不完全性腭裂患儿。比较结果显示,与唇轻微不完全性腭裂患儿相比,完全性主要腭裂患儿的蝶枕软骨结合更宽,且完全性腭裂患儿蝶枕软骨结合上部至鞍点的距离更短。这些发现可能与主要腭裂患儿软骨性颅底早期发育中的缺陷或成熟延迟有关。

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Spheno-occipital synchondrosis in three-month-old children with clefts of the lip and palate: a radiographic study.唇腭裂三个月大儿童的蝶枕软骨结合:一项影像学研究。
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引用本文的文献

1
Timing of Spheno-Occipital Synchondrosis Ossification in Children and Adolescents with Cleft Lip and Palate: A Retrospective Case-Control Study.腭裂患者蝶枕缝骨化的时间:一项回顾性病例对照研究。
Int J Environ Res Public Health. 2020 Nov 29;17(23):8889. doi: 10.3390/ijerph17238889.
2
Time and pattern of the fusion of the spheno-occipital synchondrosis in patients with skeletal Class I and Class III malocclusion.骨型Ⅰ类和Ⅲ类错(牙合)患者蝶枕结合融合的时间和模式。
Angle Orthod. 2019 May;89(3):470-479. doi: 10.2319/052218-386.1. Epub 2018 Dec 5.
3
Developmental expression of Dkk1-3 and Mmp9 and apoptosis in cranial base of mice.
Dkk1 - 3、Mmp9在小鼠颅底的发育表达及细胞凋亡
J Mol Histol. 2005 Sep;36(6-7):419-26. doi: 10.1007/s10735-005-9014-5. Epub 2006 Mar 7.