Subbanna I, de Baere T, Therasse E, Prade M, Eisele G, Roche A
Department of Radiology, Institut Gustave-Roussy, Villejuif, France.
J Vasc Interv Radiol. 1993 Nov-Dec;4(6):753-8. doi: 10.1016/s1051-0443(93)71968-5.
The reactivity and patency of balloon-expandable Strecker stents were determined in the superior vena cava (SVC) and inferior vena cava (IVC) of rabbits.
One stent was placed in each of 24 rabbits; 15 were placed in the SVC and nine in the IVC. The duration of stent placement varied between 3 days and 15 months. After the animals were killed, the segments in which the stent was placed were sectioned and analyzed under light microscopy for quantification of neointimal hyperplasia with metal struts in situ.
Twenty-three stents remained patent throughout. Two SVC stents thrombosed at 1 week; one of these recanalized spontaneously after 4 weeks. Self-limiting neointimal hyperplasia reached a maximum thickness at 1 month and receded over 3-6 months. In five rabbits with long-term SVC stents, there was a radial shift of the stent to the perivascular layer of fat. Despite this shift, these stents remain patent.
Strecker stents are well adapted to the venous system in terms of both patency and histocompatibility.
在兔的上腔静脉（SVC）和下腔静脉（IVC）中测定球囊扩张式斯特雷克支架的反应性和通畅性。
24只兔，每只植入1枚支架；15枚植入SVC，9枚植入IVC。支架植入时长在3天至15个月之间不等。处死动物后，将植入支架的节段进行切片，并在光学显微镜下分析，以量化原位金属支柱周围新生内膜增生情况。
23枚支架全程保持通畅。2枚SVC支架在1周时发生血栓形成；其中1枚在4周后自发再通。自限性新生内膜增生在1个月时达到最大厚度，并在3至6个月内消退。在5只植入长期SVC支架的兔中，支架向血管周围脂肪层发生径向移位。尽管有这种移位，这些支架仍保持通畅。
就通畅性和组织相容性而言，斯特雷克支架非常适合静脉系统。
