Conte-Devolx B, Guillaume V, Grino M, Boudouresque F, Magnan E, Cataldi M, Oliver C
Laboratoire de Neuroendocrinologie Expérimentale, INSERM U 297, Faculté de Médecine Nord, Marseille.
Encephale. 1993 Mar;19 Spec No 1:143-6.
All kind of stress produce an endocrine response. These hormonal responses can serve as stress indicators. The main peripheral endocrine responses to stress are the activation of adrenal corticoids, the stimulation of Growth Hormone (GH) and prolactin secretion, and the inhibition of insulin and gonadal secretion. Except for the inhibition of insulin release, all these hormonal variations depend on the adenohypophysis activity: stimulation of Adrenocorticotrophin hormone (ACTH), GH and prolactin, and inhibition of gonadotrophins (LH-FSH) secretions. Several lines of evidence demonstrate that specific hypothalamic Neuro-hormones stimulate or inhibit the hypophysial activity in response to stress. However, due to methodological difficulties, only measurements of peripheral hormones can be used as stress indicators.
各种应激都会产生内分泌反应。这些激素反应可作为应激指标。应激的主要外周内分泌反应是肾上腺皮质激素的激活、生长激素(GH)和催乳素分泌的刺激以及胰岛素和性腺分泌的抑制。除了胰岛素释放的抑制外,所有这些激素变化都依赖于腺垂体的活动:促肾上腺皮质激素(ACTH)、GH和催乳素的刺激以及促性腺激素(LH - FSH)分泌的抑制。多条证据表明,特定的下丘脑神经激素会响应应激刺激或抑制垂体活动。然而,由于方法上的困难,只有外周激素的测量可作为应激指标。