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The hypolipidaemic effect of gemfibrozil (CI-719) in laboratory animals.

作者信息

Rodney G, Uhlendorf P, Maxwell R E

出版信息

Proc R Soc Med. 1976;69 Suppl 2(Suppl 2):6-10. doi: 10.1177/00359157760690S203.

DOI:10.1177/00359157760690S203
PMID:828263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1864017/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6caa/1864017/7da082f2fdca/procrsmed00035-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6caa/1864017/7da082f2fdca/procrsmed00035-0013-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6caa/1864017/7da082f2fdca/procrsmed00035-0013-a.jpg

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The hypolipidaemic effect of gemfibrozil (CI-719) in laboratory animals.吉非贝齐（CI - 719）对实验动物的降血脂作用。
Proc R Soc Med. 1976;69 Suppl 2(Suppl 2):6-10. doi: 10.1177/00359157760690S203.
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A clofibrate controlled trial of gemfibrozil in the treatment of hyperlipidaemias.吉非贝齐治疗高脂血症的氯贝丁酯对照试验。
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Effect of gemfibrozil upon platelet function and blood coagulation. Preliminary report.吉非贝齐对血小板功能和血液凝固的影响。初步报告。
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Gemfibrozil and clofibrate in the treatment of hyperlipidaemias. A comparative trial.吉非贝齐和氯贝丁酯治疗高脂血症的比较试验。
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Gemfibrozil treatment: a comparison with clofibrate.
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Hypolipidaemic action of gemfibrozil in adult nephrotics.吉非贝齐对成年肾病患者的降血脂作用。
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Structure/activity relationship of gemfibrozil (CI-719) and related compounds.吉非贝齐（CI - 719）及相关化合物的构效关系。
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Effect of gemfibrozil on lipolysis in dogs in vivo.吉非贝齐对犬体内脂肪分解的影响。
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Extrinsic factors affecting the response to gemfibrozil.影响对吉非贝齐反应的外在因素。
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The use of gemfibrozil in the treatment of primary hyperlipoproteinaemia. Preliminary report.
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本文引用的文献

1
THE COMMON MODE OF ACTION OF THREE NEW CLASSES OF INHIBITORS OF CHOLESTEROL BIOSYNTHESIS.
Biochem Pharmacol. 1965 Apr;14:445-56. doi: 10.1016/0006-2952(65)90217-0.
2
INFLUENCE OF THYROID HORMONES ON L-ALPHA-GLYCEROPHOSPHATE DEHYDROGENASES AND OTHER DEHYDROGENASES IN VARIOUS ORGANS OF THE RAT.甲状腺激素对大鼠各器官中L-α-甘油磷酸脱氢酶及其他脱氢酶的影响
J Biol Chem. 1965 Mar;240:1427-36.
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The production and release of glycerol by adipose tissue incubated in vitro.体外培养的脂肪组织中甘油的产生与释放。
吉非贝齐作为晚发性婴儿神经元蜡样脂褐质沉积症及其他脂质贮积病患儿辅助治疗的安全性和潜在疗效。
Orphanet J Rare Dis. 2017 Jun 17;12(1):113. doi: 10.1186/s13023-017-0663-8.
4
Gemfibrozil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in dyslipidaemia.吉非贝齐。对其药效学和药代动力学特性以及在血脂异常治疗中的应用综述。
Drugs. 1988 Sep;36(3):314-39. doi: 10.2165/00003495-198836030-00004.
J Biol Chem. 1962 Nov;237:3354-8.
4
Studies on the mechnism of activation of acetyl coenzyme A carboxylase by citrate.关于柠檬酸激活乙酰辅酶A羧化酶机制的研究。
J Biol Chem. 1963 Feb;238:533-40.
5
A method for measurement of cholesterol in blood serum.一种测定血清中胆固醇的方法。
Clin Chem. 1961 Jun;7:275-84.
6
The enzymic composition of nuclei isolated from radio-sensitive and non-sensitive tissues with special reference to catalase activity.从放射敏感和不敏感组织中分离出的细胞核的酶组成，特别提及过氧化氢酶活性。
Biochem J. 1960 Oct;77(1):5-12. doi: 10.1042/bj0770005.
7
Acute effects of fructose and glucose on the concentration and removal rate of plasma triglyceride.果糖和葡萄糖对血浆甘油三酯浓度及清除率的急性影响。
Life Sci. 1966 Jan;5(1):89-94. doi: 10.1016/0024-3205(66)90191-3.
8
The bursa pharyngea in the giant panda (Ailuropoda melanoleuca).
Nature. 1965 Nov 27;208(5013):865-7. doi: 10.1038/208865a0.
9
Enzymatic regulation of 3-sn-phosphatidylcholine and triacylglycerol synthesis in states of altered lipid metabolism.脂质代谢改变状态下3- sn -磷脂酰胆碱和三酰甘油合成的酶促调节
J Biol Chem. 1969 Jan 25;244(2):377-83.
10
Inhibitory action of -(4-chlorophenoxy)- -methylpropionic acid analogs on cholesterol biosynthesis and lipolysis in vitro.α-(4-氯苯氧基)-α-甲基丙酸类似物对体外胆固醇生物合成及脂肪分解的抑制作用
J Med Chem. 1971 Aug;14(8):754-7. doi: 10.1021/jm00290a020.