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[30例角膜后固定人工角膜移植术的结果]

[Results of 30 keratoprostheses with retrocorneal fixation].

作者信息

Lacombe E

出版信息

J Fr Ophtalmol. 1993;16(8-9):426-34.

PMID:8282949
Abstract

Keratoprosthesis is the last solution for corneally blind patients who cannot benefit from corneal grafts. The indications are limited to blind patients with monophthalmia and bilateral problems that are otherwise untreatable. After implanting the Choyce and Strampelli's devices for more than 10 years, we abandoned these anterior fixation techniques and now use a keratoprosthesis in which the sole mechanical fixation consists of a posterior support which is subsequently sealed by the fibrosis produced by the endothelial-Descement tissues. This new prosthesis is made of two pieces, an optic and an haptic fashioned out of CQ-PMMA. To minimize expulsion, the haptic outer diameter is greater than the central corneal orifice through which the optic is inserted and screwed into the haptic. The keratoprosthesis refractive power can be easily adjusted after lensectomy by changing the 40 D for a 63 D optic. The prosthesis is implanted in a single step surgical procedure, and can be implanted in phakic eyes while respecting the physiology and anatomy of these fragile eyes. This single step procedure reduces the usual repeated operations required when using, other techniques. We operated 12 cases of pseudopemphigus, 9 cases of burns, 7 cases of trachoma, and 2 cases of pseudophakic oedema with good cosmetic and visual results with a follow-up ranging from several months to more than 3 years. The results obtained with this new keratoprosthesis are encouraging. The results have been analysed and classified into: anatomic and functional success 20 cases, anatomic success and functional failures 4 cases, anatomic failures 6 cases.

摘要

角膜移植术是无法从角膜移植中获益的角膜盲患者的最终解决方案。其适应症仅限于单眼失明以及双侧问题导致的失明患者,这些情况用其他方法无法治疗。在植入乔伊斯(Choyce)和斯特兰佩利(Strampelli)的装置超过10年后,我们放弃了这些前部固定技术,现在使用一种角膜移植术,其唯一的机械固定方式是后部支撑,随后由内皮-后弹力层组织产生的纤维化将其密封。这种新的假体由两部分组成,一个光学部分和一个由CQ - 聚甲基丙烯酸甲酯制成的触觉部分。为了尽量减少排斥反应,触觉部分的外径大于插入光学部分并与之拧紧的中央角膜孔。通过将40 D的光学部分换成63 D,在晶状体切除术后可以轻松调整角膜移植术的屈光力。该假体通过单步手术植入,并且可以在保留这些脆弱眼睛的生理和解剖结构的同时植入有晶状体眼。这种单步手术减少了使用其他技术时通常需要的重复手术。我们对12例类天疱疮、9例烧伤、7例沙眼和2例假晶状体水肿患者进行了手术,随访时间从几个月到3年多,获得了良好的美容和视觉效果。使用这种新的角膜移植术获得的结果令人鼓舞。结果已被分析并分类为:解剖和功能成功20例,解剖成功但功能失败4例,解剖失败6例。

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