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少菌型麻风中的菌血症与麻风分枝杆菌细胞壁抗原

Bacillaemia and Mycobacterium leprae cell wall antigen in paucibacillary leprosy.

作者信息

Kaur I, Kaur S, Sharma V K, Agnihotri N, Vaishnavi C, Ganguly N K

机构信息

Dept of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh.

出版信息

Indian J Lepr. 1993 Jul-Sep;65(3):283-8.

PMID:8283063
Abstract

A study was undertaken to estimate bacillaemia and M. leprae antigen detection in 54 paucibacillary leprosy patients (TT, BT). Acid-fast bacilli were detected in the blood of 14.8% patients of borderline tuberculoid (BT) leprosy. M. leprae antigen was demonstrated in 48.2% patients of BT leprosy. Slit-skin smears were negative in all these patients. At the end of treatment (6 months of WHO-MDT) all the follow-up blood samples were negative for both bacillaemia and M. leprae antigen in the serum.

摘要

开展了一项研究,以评估54例少菌型麻风患者(结核样型、界线类结核样型)的菌血症及麻风杆菌抗原检测情况。在界线类结核样型(BT)麻风患者中,14.8%的患者血液中检测到抗酸杆菌。48.2%的BT麻风患者检测到麻风杆菌抗原。所有这些患者的皮肤涂片均为阴性。治疗结束时(世界卫生组织多药联合化疗6个月),所有随访血样的菌血症及血清中的麻风杆菌抗原均为阴性。

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