Corba J, Pacenovský J, Krupicer I, Breza M, Popovic S, Reisz T
Vet Med (Praha). 1976;21(8):461-5.
The paper reports on the results of the clinical tests for the effectiveness of oxyclozanide pure substance (produced by ICI, U.K.) in cattle naturally invaded by the paramphistomata Liorchis scotiae. Helminthological dissection, performed 21 days after a single application of 15 mg oxyclozanide per 1 kg 1. w., revealed 87.5% intenseffectiveness on sexually mature paramphistomata on 85% intenseffectiveness on juvenile paramphistomata. The extenseffectiveness of the chemical was equal to zero. The coprological examinations performed for the three weeks in one-week intervals after therapy showed a decline in the number of produced eggs. The animals were given the medicated feed containing oxyclozanide only after preceding starvation. The chemical did not produce any unfavourable side effects or signs.
该论文报道了氧氯苯酰纯物质（由英国帝国化学工业公司生产）对自然感染斯氏梨形双腔吸虫的牛进行临床试验的结果。在每1千克体重单次施用15毫克氧氯苯酰21天后进行的蠕虫学解剖显示，对性成熟的双腔吸虫的驱虫有效率为87.5%，对幼年双腔吸虫的驱虫有效率为85%。该化学药物的广效性为零。治疗后每隔一周进行为期三周的粪便学检查显示，产卵数量有所下降。这些动物仅在先前禁食后才给予含有氧氯苯酰的药饵。该化学药物未产生任何不良副作用或体征。
