Kuijpers D, Kruyt R H, Oudkerk M
Department of Diagnostic Radiology, Dr. Daniël den Hoed Cancer Center, Rotterdam, The Netherlands.
J Urol. 1994 Feb;151(2):326-8. doi: 10.1016/s0022-5347(17)34938-8.
In a prospective study, 84 nonanechoic renal masses were examined with duplex Doppler ultrasound with a 3.5 mHz. transducer. This study included malignant lesions in 49 cases (30 renal carcinomas, 9 metastases, 8 lymphomas and 2 sarcomas) and benign lesions in 35 (18 complicated cysts, 6 inflammatory processes, 5 columns of Bertin, 3 angiomyolipomas and 3 hematomas). We analyzed whether duplex Doppler ultrasound can have a role in the differential diagnoses of these solid renal masses. Renal carcinomas demonstrated Doppler shifts of 2.5 kHz. or more in 23 cases (77%). These masses had significantly higher Doppler shifts than all of the other malignant masses (p < 0.001). Among the benign lesions the Doppler shifts were less than 2.5 kHz. in 33 cases (84%). The 2 masses with a Doppler shift of more than 2.5 kHz. in this group were inflammatory lesions. Detection of a Doppler shift of 2.5 or greater in a renal mass supports suspicion of a renal cell carcinoma, although an inflammatory process may also produce such a high Doppler shift. Doppler shifts of less than 2.5 kHz. in solid renal masses support the diagnoses of a benign lesion and a malignant lesion other than renal cell carcinoma.
在一项前瞻性研究中,使用3.5兆赫兹的探头,通过双功多普勒超声对84个无回声肾肿块进行了检查。该研究包括49例恶性病变(30例肾癌、9例转移瘤、8例淋巴瘤和2例肉瘤)和35例良性病变(18例复杂性囊肿、6例炎症性病变、5例肾柱肥大、3例血管平滑肌脂肪瘤和3例血肿)。我们分析了双功多普勒超声在这些实性肾肿块的鉴别诊断中是否能发挥作用。23例(77%)肾癌表现出2.5千赫兹或更高的多普勒频移。这些肿块的多普勒频移显著高于所有其他恶性肿块(p<0.001)。在良性病变中,33例(84%)的多普勒频移小于2.5千赫兹。该组中多普勒频移大于2.5千赫兹的2个肿块为炎症性病变。肾肿块中检测到2.5或更高的多普勒频移支持怀疑为肾细胞癌,尽管炎症性病变也可能产生如此高的多普勒频移。实性肾肿块中多普勒频移小于2.5千赫兹支持诊断为良性病变和非肾细胞癌的恶性病变。