Lapeyre-Mestre M, Daly-Schveitzer N, Boussin G, Delande G
Département d'Information Médicale, Centre Claudius Regaud, Toulouse.
Rev Epidemiol Sante Publique. 1993;41(5):397-406.
We describe a retrospective and comparative assessment of the medical care of breast cancer among women in a French comprehensive cancer center, the Centre Claudius Regaud. There was no significant difference for the clinical results between two cohorts of women, treated in 1975 and 1985 respectively, for equivalent stages of disease. The overall increase in survival resulted mainly from early diagnosis. Locoregional treatment cost and conservative treatment cost, from official Social Security costs, did not increase between the two periods. However, a high risk of metastasis risk during the first treatment, or recurrence during the follow-up, resulted in differences in cost-effectiveness between 1975 and 1985. Although these results must be interpreted with caution, this analysis raises strategic questions about the suitability of some medical practices, particularly in the care of evolutive neoplasm.
我们描述了在法国综合癌症中心克劳迪乌斯·雷加德中心对乳腺癌女性患者医疗护理进行的一项回顾性比较评估。在疾病分期相同的情况下，分别于1975年和1985年接受治疗的两组女性患者的临床结果没有显著差异。生存率的总体提高主要源于早期诊断。两个时期之间，来自官方社会保障费用的局部区域治疗成本和保守治疗成本并未增加。然而，首次治疗期间转移风险高或随访期间复发导致了1975年和1985年之间成本效益的差异。尽管这些结果必须谨慎解读，但该分析提出了关于某些医疗实践适用性的战略问题，尤其是在进展性肿瘤的护理方面。
