Albanese C T, Wiener E S
Department of Pediatric Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pennsylvania 15213-2583.
Semin Surg Oncol. 1993 Nov-Dec;9(6):467-77. doi: 10.1002/ssu.2980090604.
Long-term central venous access is an integral part of the management of many, but not all children with cancer. The proper selection of those children who require this access and which access device (external vs. totally implanted) is best suited to that child is important to minimize complications and obtain optimal results. Although most of these devices can be expected to last the duration of the treatment protocol or the patient's life, complications (infection, occlusion, dislodgment) occur with higher than desired frequency, infection being the most common. No measures are clearly beneficial in preventing infection, but most infections can be treated successfully without device removal. Premature removal or dislodgement occurs more frequently with external catheters and may be minimized by techniques used at insertion. Occlusion, detected early, can be successfully managed by clot lysis in most children.
长期中心静脉通路是许多(但并非所有)癌症患儿治疗管理的一个重要组成部分。正确选择那些需要这种通路的患儿以及哪种通路装置(外置式与完全植入式)最适合该患儿,对于将并发症降至最低并取得最佳效果至关重要。尽管预计这些装置中的大多数能够使用整个治疗疗程或患者的一生,但并发症(感染、堵塞、移位)的发生频率高于预期,其中感染最为常见。目前尚无明确有效的预防感染措施,但大多数感染在不拔除装置的情况下能够成功治疗。外置导管更容易出现过早拔除或移位的情况,可通过插入时采用的技术将其降至最低。大多数患儿若能早期发现堵塞,通过血栓溶解可成功处理。