Albrecht S, Hicks M J, Antalffy B
Department of Pathology, Baylor College of Medicine, Houston, Texas.
Surgery. 1994 Jan;115(1):1-6.
Coccygodynia is an uncommon condition of diverse causes. A few cases were attributed to so-called pericoccygeal glomus tumors. However, the pericoccygeal soft tissues normally contain numerous small glomus bodies and a larger one known as the glomus coccygeum, which can reach several millimeters in diameter. Most reported cases of alleged pericoccygeal glomus tumors represent normal, incidentally discovered coccygeal glomus bodies. Recently, an intracoccygeal glomus tumor was reported as a cause of coccygodynia. However, we suspected that glomera can also occur normally within the coccyx itself.
Twenty coccyges from fetuses, newborns, infants, and adults were obtained at autopsy, embedded in toto, and examined histologically in step sections.
Intracoccygeal glomera were present in six of the nine pediatric specimens and all 11 adult specimens. All were microscopic structures, and none appeared to have caused bony destruction or erosion. They did not differ from the structures previously reported as alleged intracoccygeal "glomus tumors."
Pericoccygeal and intracoccygeal glomus bodies are normal findings in humans at all ages. They should not be mistaken for tumors, and their role in the pathogenesis of coccygodynia is questionable.
尾骨痛是一种病因多样的罕见病症。少数病例被归因于所谓的尾骨周围血管球瘤。然而,尾骨周围软组织通常含有众多小的血管球小体以及一个较大的称为尾骨血管球的结构,其直径可达数毫米。大多数报道的所谓尾骨周围血管球瘤病例实际上是正常的、偶然发现的尾骨血管球小体。最近,有报道称尾骨内血管球瘤是尾骨痛的一个病因。然而,我们怀疑血管球也可能正常地出现在尾骨本身内部。
从胎儿、新生儿、婴儿和成人的尸体解剖中获取20个尾骨,整体包埋,并进行连续切片的组织学检查。
9个儿科标本中的6个以及所有11个成人标本中都存在尾骨内血管球。所有都是微观结构,且似乎均未引起骨质破坏或侵蚀。它们与先前报道的所谓尾骨内“血管球瘤”结构并无差异。
尾骨周围和尾骨内血管球小体在各年龄段人群中均为正常发现。它们不应被误诊为肿瘤,其在尾骨痛发病机制中的作用也值得怀疑。