[Effect of nitrobenzenes on methemoglobin formation and activity of antioxidative enzymes in mouse erythrocytes].

The mice intoxication with intraperitoneal introduction of 1,3,5-trinitrobenzene and 2,4,6-trinitrotoluene causes an increase of methemoglobin and a decrease of glutathione level. But intoxication by polynitrobenzenes exerts no effect on the total level of SH-groups. A small increase in total activity of dehydrogenases of the pentose phosphate way in response to 2,4,6-trinitrotoluene intoxication is also revealed. The level of both lipid peroxidation, superoxide dismutase and catalase activity is not influenced by 2,4,6-trinitrotoluene and 1,3,5-trinitrobenzene.