Nekliudova L I, Fedorova Iu B, Pasternak N A, Shenderovich V A, Petrushanskaia G A
Antibiotiki. 1976 Dec;21(12):1116-21.
The efficacy of aerosols of leukocytal interferon used in complex with antibacterial and other medicamentous agents was studied during influenza epidemic in 1975 due to Port-Chalmers virus of influenza A with increased numbers of viral-bacterial pneumonia. The viral-sta-phylococcal etiology of the infection was confirmed in 80 per cent of the cases under stationary conditions. Various microorganism and most often Staph aureus were isolated in addition to the viruses from the patient's sputum and washings and their antibioticograms were determined. The studies showed that the complex treatment of the patients with virologically and serologically confirmed diagnosis of the disease resulted in decreased duration of the disease, less pronounced intoxication and more rapid resorption of the changes in the lung tissue.
1975年流感流行期间,对白细胞干扰素气雾剂与抗菌及其他药物联合使用的疗效进行了研究,此次流感由甲型流感的波特-查尔默斯病毒引起,病毒-细菌性肺炎病例增多。在住院条件下,80%的病例证实了感染的病毒-葡萄球菌病因。除病毒外,还从患者痰液和冲洗液中分离出各种微生物,最常见的是金黄色葡萄球菌,并测定了它们的抗菌谱。研究表明,对经病毒学和血清学确诊的患者进行综合治疗,可缩短病程,减轻中毒症状,并使肺组织病变更快吸收。