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间质性膀胱炎的外科治疗

Surgical management of interstitial cystitis.

作者信息

Irwin P P, Galloway N T

机构信息

Department of Surgery, Emory University School of Medicine, Atlanta, Georgia.

出版信息

Urol Clin North Am. 1994 Feb;21(1):145-51.

PMID:8284838
Abstract

For most urologists the decision to operate on a patient with interstitial cystitis is made with extreme caution. The knowledge that this is a nonmalignant disease, that it poses little risk to overall health (although most patients would differ with this assertion), and that surgical intervention may be accompanied by additional complications has relegated open surgical procedures to last on the list of treatments for interstitial cystitis. This reluctance to operate until late in the course of the disease is clearly unsatisfactory. If a successful surgical procedure can performed, it ought to be employed early in the course of the patient's management and not withheld after the unfortunate patient has been subjected to a host of unsatisfactory conservative treatments. There is a need for balance between timidity and surgical aggression in the management of this dreadful condition. There is a need to identify the appropriate patients for surgical treatment and to select the most successful procedure. We should not expect to have to move through a series of different procedures for each patient, but rather select the right one the first time. There is an obvious need for a better understanding of the precise cause and pathogenesis of the condition so that alternative forms of treatment may be investigated. Surgery can provide significant relief for many patients with incapacitating symptoms. Cystectomy, either supratrigonal or total, is best reserved for those patients with markedly reduced bladder capacities.

摘要

对于大多数泌尿科医生来说,决定对间质性膀胱炎患者进行手术时会极其谨慎。鉴于这是一种非恶性疾病,对整体健康构成的风险较小(尽管大多数患者可能不同意这一说法),而且手术干预可能会伴有其他并发症,开放性手术已被列为间质性膀胱炎治疗方法中的最后选择。这种在疾病晚期才愿意进行手术的做法显然不尽人意。如果能够实施成功的手术,就应该在患者治疗过程的早期采用,而不是在不幸的患者接受了一系列不理想的保守治疗之后才进行。在这种可怕疾病的治疗中,需要在胆怯和积极手术之间找到平衡。需要确定适合手术治疗的患者,并选择最成功的手术方法。我们不应期望为每个患者都依次采用一系列不同的手术,而应一次性选择正确的手术。显然需要更好地了解该病的确切病因和发病机制,以便研究其他治疗形式。手术可以为许多有严重症状的患者提供显著缓解。膀胱部分切除术(三角区上方或全膀胱切除)最好仅用于膀胱容量明显减小的患者。

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