Vitellozzi G, Mughetti L, Palmarini M, Mandara M T, Mechelli L, Sharp J M, Manocchio I
Istituto di Patologia Generale ed Anatomia Patologica Veterinaria, Facoltà di Medicina Veterinaria, Università di Perugia, Italy.
Zentralbl Veterinarmed B. 1993 Sep;40(7):459-68. doi: 10.1111/j.1439-0450.1993.tb00164.x.
An outbreak of enzootic intranasal tumour (EIT) in a goat herd in Central Italy is described. From October 1990 to September 1992 41 tumors were diagnosed in goats ranging in age from 6 months to 6 years and of both the Alpine and Saanen breeds. Clinically the affected goats showed nasal discharge, facial swelling, sneezing and snoring respiration and weight loss. Post-mortem examinations revealed uni- or bilateral tumours of the olfactory mucous membrane. The neoplasms were classified as low grade adenocarcinomas. Ultrastructurally, retrovirus-like particles were observed in 10/10 tumours examined. Epidemiological and ultrastructural findings strongly suggest a viral aetiology for intranasal enzootic adenocarcinoma in the goats examined.
本文描述了意大利中部一个山羊群中发生的地方性鼻内肿瘤（EIT）疫情。从1990年10月到1992年9月，在年龄从6个月到6岁的山羊中诊断出41个肿瘤，这些山羊包括阿尔卑斯和萨能两个品种。临床上，患病山羊表现出鼻分泌物、面部肿胀、打喷嚏、打鼾呼吸和体重减轻。尸检发现嗅粘膜有单侧或双侧肿瘤。这些肿瘤被分类为低级别腺癌。超微结构上，在检查的10个肿瘤中有10个观察到类似逆转录病毒的颗粒。流行病学和超微结构研究结果强烈表明，所检查山羊的鼻内地方性腺癌是由病毒引起的。
Zotero 插件