Chauhan A, Mullins P A, Thuraisingham S, Taylor G, Petch M C, Schofield P M
Cardiac Unit, Papworth Hospital, Cambridge, England.
Angiology. 1993 Dec;44(12):939-44. doi: 10.1177/000331979304401203.
The authors assessed whether measurements obtained by Judkins-style Doppler catheters are comparable to those achieved with the intracoronary Doppler technique in 42 patients with normal coronary arteries on angiography (19 syndrome X and 23 heart transplant patients). Resting coronary flow velocity and response to a hyperemic intracoronary dose of papaverine was measured with a Judkins-style, 8F Doppler-tipped catheter positioned in the left coronary ostium and a 3.6F intracoronary Doppler catheter positioned in the proximal left anterior descending artery. Mean coronary flow velocity at rest was significantly higher with the Judkins Doppler (10.1 +/- 4.6 vs 6.3 +/- 4.5 cm/sec, p < 0.01). The mean coronary flow velocity at peak hyperemia was also significantly higher with the Judkins Doppler (33.7 +/- 14.1 vs 19.7 +/- 11.5 cm/sec, p < 0.01). Coronary flow reserve was 3.57 +/- 1.3 with the Judkins Doppler and 3.47 +/- 1.2 with the intracoronary Doppler (r = 0.85). A second study was performed in 14 heart transplant patients with the intracoronary Doppler positioned in the left main coronary artery. The resting and hyperemic flow velocities were again higher with the Judkins Doppler but the differences were not statistically significant. There was again a strong correlation between the Doppler catheters for coronary flow reserve measurements. The Judkins-style Doppler technique appears to be a quick, safe, and accurate alternative to the intracoronary Doppler technique.
作者评估了在42例血管造影显示冠状动脉正常的患者（19例X综合征患者和23例心脏移植患者）中，使用Judkins式多普勒导管获得的测量结果是否与冠状动脉内多普勒技术所取得的结果具有可比性。使用置于左冠状动脉口的Judkins式8F多普勒尖端导管和置于左前降支近端的3.6F冠状动脉内多普勒导管，测量静息冠状动脉血流速度以及对冠状动脉内注射罂粟碱充血剂量的反应。Judkins多普勒测量的静息平均冠状动脉血流速度显著更高（10.1±4.6 vs 6.3±4.5 cm/秒，p<0.01）。充血高峰时的平均冠状动脉血流速度Judkins多普勒测量结果也显著更高（33.7±14.1 vs 19.7±11.5 cm/秒，p<0.01）。Judkins多普勒测量的冠状动脉血流储备为3.57±1.3，冠状动脉内多普勒测量的为3.47±1.2（r = 0.85）。对14例心脏移植患者进行了第二项研究，冠状动脉内多普勒置于左主冠状动脉。Judkins多普勒测量的静息和充血血流速度再次更高，但差异无统计学意义。两种多普勒导管测量冠状动脉血流储备再次具有很强的相关性。Judkins式多普勒技术似乎是冠状动脉内多普勒技术的一种快速、安全且准确的替代方法。
