使用钆喷酸葡胺增强磁共振成像精确评估与继发性心肌病相关的心肌损伤。

Precise assessment of myocardial damage associated with secondary cardiomyopathies by use of Gd-DTPA-enhanced magnetic resonance imaging.

作者信息

Matsuoka H, Hamada M, Honda T, Kawakami H, Okayama H, Abe M, Shigematsu Y, Sumimoto T, Hiwada K

机构信息

2nd Department of Internal Medicine, Ehime University School of Medicine, Japan.

出版信息

Angiology. 1993 Dec;44(12):945-50. doi: 10.1177/000331979304401204.

DOI:10.1177/000331979304401204

PMID:8285371

Abstract

To evaluate the myocardial damage in patients with secondary cardiomyopathies, the authors examined gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced magnetic resonance imaging (MRI) in 5 patients (2 with cardiac amyloidosis, 2 with acute myocarditis, 1 with cardiac thyrotoxicosis). MR images were performed at 1.5-T by using a spin echo pulse sequence before and after intravenous administration of Gd-DTPA (0.2 mmol/kg). All patients revealed distinct high-intensity areas on postcontrast images. Moreover, MRI with Gd-DTPA could determine the severity and precise regions of myocardial damage associated with secondary cardiomyopathies. It is suggested that gated cardiac MRI with Gd-DTPA enhancement is useful for detecting the myocardial damage in secondary cardiomyopathies.

摘要

为评估继发性心肌病患者的心肌损伤情况，作者对5例患者（2例心脏淀粉样变性、2例急性心肌炎、1例心脏甲状腺毒症）进行了钆喷酸葡胺（Gd-DTPA）增强磁共振成像（MRI）检查。在静脉注射Gd-DTPA（0.2 mmol/kg）前后，采用自旋回波脉冲序列于1.5-T磁场下进行MR成像。所有患者在造影后图像上均显示出明显的高强度区域。此外，Gd-DTPA增强MRI能够确定与继发性心肌病相关的心肌损伤的严重程度和精确区域。提示Gd-DTPA增强门控心脏MRI有助于检测继发性心肌病中的心肌损伤。