Matsuoka H, Hamada M, Honda T, Kawakami H, Okayama H, Abe M, Shigematsu Y, Sumimoto T, Hiwada K
2nd Department of Internal Medicine, Ehime University School of Medicine, Japan.
Angiology. 1993 Dec;44(12):945-50. doi: 10.1177/000331979304401204.
To evaluate the myocardial damage in patients with secondary cardiomyopathies, the authors examined gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced magnetic resonance imaging (MRI) in 5 patients (2 with cardiac amyloidosis, 2 with acute myocarditis, 1 with cardiac thyrotoxicosis). MR images were performed at 1.5-T by using a spin echo pulse sequence before and after intravenous administration of Gd-DTPA (0.2 mmol/kg). All patients revealed distinct high-intensity areas on postcontrast images. Moreover, MRI with Gd-DTPA could determine the severity and precise regions of myocardial damage associated with secondary cardiomyopathies. It is suggested that gated cardiac MRI with Gd-DTPA enhancement is useful for detecting the myocardial damage in secondary cardiomyopathies.
为评估继发性心肌病患者的心肌损伤情况，作者对5例患者（2例心脏淀粉样变性、2例急性心肌炎、1例心脏甲状腺毒症）进行了钆喷酸葡胺（Gd-DTPA）增强磁共振成像（MRI）检查。在静脉注射Gd-DTPA（0.2 mmol/kg）前后，采用自旋回波脉冲序列于1.5-T磁场下进行MR成像。所有患者在造影后图像上均显示出明显的高强度区域。此外，Gd-DTPA增强MRI能够确定与继发性心肌病相关的心肌损伤的严重程度和精确区域。提示Gd-DTPA增强门控心脏MRI有助于检测继发性心肌病中的心肌损伤。
