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鞘氨醇单胞菌属菌株SS33对4,4'-和2,4-二卤代二苯醚的生物降解与转化

Biodegradation and transformation of 4,4'- and 2,4-dihalodiphenyl ethers by Sphingomonas sp. strain SS33.

作者信息

Schmidt S, Fortnagel P, Wittich R M

机构信息

Institut für Allgemeine Botanik, Universität Hamburg, Germany.

出版信息

Appl Environ Microbiol. 1993 Nov;59(11):3931-3. doi: 10.1128/aem.59.11.3931-3933.1993.

DOI:10.1128/aem.59.11.3931-3933.1993
PMID:8285696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC182552/
Abstract

The bacterium Sphingomonas sp. strain SS33, obtained from parent diphenyl ether-mineralizing strain SS3 (S. Schmidt, R.-M. Wittich, D. Erdmann, H. Wilkes, W. Francke, and P. Fortnagel, Appl. Environ. Microbiol. 58:2744-2750, 1992) after several weeks of adaptation on 4,4'-difluorodiphenyl ether as the new target compound, also utilized 4,4'-dichlorodiphenyl ether for growth. Intermediary halocatechols were also mineralized via the ortho pathway by type I enzymes. 4,4'-Dibromodiphenyl ether was not used as a carbon source although transformation by resting cells yielded mononuclear haloaromatic compounds, such as 4-bromophenol and 4-bromocatechol. The same was true for the conversion of 2,4-dichlorodiphenyl ether, which yielded the respective (halo-) phenols and (halo-) catechols.

摘要

从亲本二苯醚矿化菌株SS3(S. Schmidt、R.-M. Wittich、D. Erdmann、H. Wilkes、W. Francke和P. Fortnagel,《应用与环境微生物学》58:2744 - 2750,1992年)经数周在4,4'-二氟二苯醚作为新目标化合物上适应后获得的鞘氨醇单胞菌属菌株SS33,也利用4,4'-二氯二苯醚进行生长。中间卤代邻苯二酚也通过I型酶经由邻位途径矿化。4,4'-二溴二苯醚虽未用作碳源,但静息细胞转化产生了单核卤代芳烃化合物,如4-溴苯酚和4-溴邻苯二酚。2,4-二氯二苯醚的转化情况也是如此,其产生了相应的(卤代)酚和(卤代)邻苯二酚。

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