Vandenesch F, Etienne J, Reverdy M E, Eykyn S J
Laboratoire de Bactériologie, Hôpital Louis Pradel, Lyon, France.
Clin Infect Dis. 1993 Nov;17(5):871-6. doi: 10.1093/clinids/17.5.871.
Staphylococcus lugdunensis is a recently described coagulase-negative staphylococcus that has been associated with human infections, including nine reported cases of infective endocarditis. The present study describes 11 other cases of infective endocarditis caused by this organism. The infection occurred in patients whose mean age was 61 years and was community-acquired in most cases. A preexisting cardiac abnormality was present in eight patients. Three of the 11 infections involved prosthetic valves. Ten strains were susceptible to penicillin. The destructive course of the infection, the need for valve replacement, and the high mortality suggest that S. lugdunensis causes a virulent form of endocarditis.
路邓葡萄球菌是一种最近才被描述的凝固酶阴性葡萄球菌，它与人类感染有关，包括9例报告的感染性心内膜炎病例。本研究描述了另外11例由该菌引起的感染性心内膜炎病例。感染发生在平均年龄为61岁的患者中，大多数病例为社区获得性感染。8名患者存在先前的心脏异常。11例感染中有3例涉及人工瓣膜。10株菌株对青霉素敏感。感染的破坏性病程、瓣膜置换的必要性以及高死亡率表明，路邓葡萄球菌可引起一种恶性的心内膜炎。
