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[电复律治疗心房颤动的即刻及长期疗效]

[The immediate and long-term efficacy of electrical cardioversion in atrial fibrillation].

作者信息

Frabetti L, Carioli E, Antonioli P, Ferrari G, Magnani B

机构信息

Istituto di Malattie dell'Apparato Cardiovasculare, Università degli Studi, Bologna.

出版信息

Cardiologia. 1993 Sep;38(9):561-7.

PMID:8287385
Abstract

With the aim to identify short- and long-term features predictive of successful electric cardioversion in stable atrial fibrillation, 186 consecutive patients submitted to electric cardioversion were reviewed. The following parameters were considered: age, atrial fibrillation duration, previous atrial fibrillation episodes, echocardiographic left atrial diameter, pre-treatment and prophylaxis with amiodarone. The patients were divided in 3 groups: Group I included 97 patients with mitral valve disease or mitral prosthesis, Group II included 27 patients with lone atrial fibrillation and Group III included 62 patients with different heart and extracardiac diseases. The electric cardioversion restored sinus rhythm in 155 patients (83%). The failure of the electric cardioversion was related only to a longer atrial fibrillation duration and to pre-treatment with amiodarone. Moreover, the failure of the electric cardioversion was more frequent in Group II patients (with lone atrial fibrillation) than in Group I patients (mitral disease or prosthesis; p < 0.005). Only for Group I patients failure of the cardioversion was related to a larger left atrium diameter (p < 0.05). Eighty-nine (57%) of the 155 patients converted to sinus rhythm were followed for at least 1 year. At 1 year sinus rhythm persisted in 57 patients (64%), and prophylaxis with amiodarone was the only predictor of sinus rhythm persistence (p < 0.05). Out of 68 patients with a 3 year follow-up, 29% still showed sinus rhythm after a single cardioversion and 37% after 2 or more cardioversions; after 5 years, out of 58 patients, those showing sinus rhythm were 6 (10.3%) and 9 (16%) respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了确定稳定型心房颤动成功进行心脏电复律的短期和长期预测特征,我们回顾了186例连续接受心脏电复律的患者。考虑了以下参数:年龄、房颤持续时间、既往房颤发作次数、超声心动图测量的左心房直径、胺碘酮的预处理和预防用药情况。患者分为3组:第一组包括97例患有二尖瓣疾病或二尖瓣人工瓣膜的患者,第二组包括27例孤立性房颤患者,第三组包括62例患有不同心脏和心脏外疾病的患者。155例患者(83%)通过心脏电复律恢复了窦性心律。心脏电复律失败仅与较长的房颤持续时间和胺碘酮预处理有关。此外,心脏电复律失败在第二组患者(孤立性房颤)中比在第一组患者(二尖瓣疾病或人工瓣膜;p<0.005)中更常见。仅对于第一组患者,电复律失败与较大的左心房直径有关(p<0.05)。155例恢复窦性心律的患者中有89例(57%)接受了至少1年的随访。1年后,57例患者(64%)维持窦性心律,胺碘酮预防用药是窦性心律维持的唯一预测因素(p<0.05)。在68例接受3年随访的患者中,单次电复律后仍有窦性心律的占29%,2次或更多次电复律后为37%;5年后,在58例患者中,仍有窦性心律的分别为6例(10.3%)和9例(16%)。(摘要截断于250字)

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