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Failure in IgA secretion by surface IgA-positive B cells in common variable immunodeficiency (CVID).常见可变免疫缺陷（CVID）中表面IgA阳性B细胞的IgA分泌失败。
Clin Exp Immunol. 1994 Jan;95(1):10-3. doi: 10.1111/j.1365-2249.1994.tb06007.x.
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Effects of 17 beta-oestradiol on function of lymphocytes from normal donors and patients with common variable immunodeficiency (CVID).17β-雌二醇对正常供体及常见变异型免疫缺陷（CVID）患者淋巴细胞功能的影响。
Clin Exp Immunol. 1994 Nov;98(2):203-9. doi: 10.1111/j.1365-2249.1994.tb06126.x.
3
Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency.白细胞介素-21可在体外恢复常见变异型免疫缺陷和选择性IgA缺陷患者的免疫球蛋白产生。
Blood. 2009 Nov 5;114(19):4089-98. doi: 10.1182/blood-2009-02-207423. Epub 2009 Sep 8.
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Grouping of patients with common variable immunodeficiency based on immunoglobulin biosynthesis: comparison with a classification system on CD4-naïve cells.基于免疫球蛋白生物合成对常见可变免疫缺陷患者进行分组：与CD4初始细胞分类系统的比较。
Immunol Lett. 2007 Dec 15;114(2):103-9. doi: 10.1016/j.imlet.2007.09.006. Epub 2007 Oct 11.
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Duodenal plasma cells correspond to serum IgA in common variable immunodeficiency.在常见可变免疫缺陷中，十二指肠浆细胞与血清IgA相对应。
Pathology. 2021 Jun;53(4):503-507. doi: 10.1016/j.pathol.2020.08.014. Epub 2020 Nov 18.
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Defective interleukin-2 and interferon-gamma gene expression in response to antigen in a subgroup of patients with common variable immunodeficiency.常见可变免疫缺陷患者亚组中，针对抗原的白细胞介素-2和干扰素-γ基因表达存在缺陷。
J Allergy Clin Immunol. 1993 Aug;92(2):340-52. doi: 10.1016/0091-6749(93)90178-i.
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Intestinal B cell defects in common variable immunodeficiency.常见变异型免疫缺陷中的肠道B细胞缺陷。
Clin Exp Immunol. 1994 Feb;95(2):215-21. doi: 10.1111/j.1365-2249.1994.tb06513.x.
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Intravenous immunoglobulin replacement therapy in the treatment of patients with common variable immunodeficiency disease: an open-label prospective study.静脉注射免疫球蛋白替代疗法治疗普通变异性免疫缺陷病患者：一项开放性前瞻性研究。
Clin Drug Investig. 2011;31(5):299-307. doi: 10.1007/BF03256928.
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Human low molecular weight B cell growth factor induces surface IgM+/A- B cells to express and secrete IgA.人低分子量B细胞生长因子诱导表面IgM+/A- B细胞表达和分泌IgA。
J Immunol. 1992 Sep 1;149(5):1771-8.
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Classification of common variable immunodeficiencies using flow cytometry and a memory B-cell functionality assay.采用流式细胞术和记忆 B 细胞功能测定对常见可变免疫缺陷进行分类。
J Allergy Clin Immunol. 2015 Jan;135(1):198-208. doi: 10.1016/j.jaci.2014.06.022. Epub 2014 Aug 10.
引用本文的文献
1
Ill-defined germinal centers and severely reduced plasma cells are histological hallmarks of lymphadenopathy in patients with common variable immunodeficiency.生发中心界限不清和浆细胞严重减少是常见可变免疫缺陷患者淋巴结病的组织学特征。
J Clin Immunol. 2014 Aug;34(6):615-26. doi: 10.1007/s10875-014-0052-1. Epub 2014 May 2.
2
Genetics of IgA deficiency and common variable immunodeficiency.IgA缺乏症和常见变异型免疫缺陷的遗传学
Clin Rev Allergy Immunol. 2000 Oct;19(2):127-40. doi: 10.1385/CRIAI:19:2:127.
3
Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID).选择性IgA缺乏症（SIgAD）和常见变异型免疫缺陷病（CVID）。
Clin Exp Immunol. 2000 May;120(2):225-31. doi: 10.1046/j.1365-2249.2000.01131.x.
本文引用的文献
1
Functional 'immaturity' of isolated B cells from patients with hypogammaglobulinaemia.低丙种球蛋白血症患者分离出的B细胞的功能性“不成熟”
Clin Exp Immunol. 1980 Dec;42(3):535-44.
2
B and T cell markers in human proliferative blood diseases and primary immunodeficiencies, with special reference to membrane bound immunoglobulins.人类增殖性血液疾病和原发性免疫缺陷中的B细胞和T细胞标志物，特别提及膜结合免疫球蛋白。
Transplant Rev. 1973;16:85-113. doi: 10.1111/j.1600-065x.1973.tb00118.x.
3
Immunoglobulins on the surface of lymphocytes in fifty patients with primary immunodeficiency diseases.五十例原发性免疫缺陷病患者淋巴细胞表面的免疫球蛋白
Clin Immunol Immunopathol. 1973 Jan;1(2):241-56. doi: 10.1016/0090-1229(73)90025-1.
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Phenotypically immature IgG-bearing B cells in patients with hypogammaglobulinemia.
J Clin Immunol. 1986 Jan;6(1):21-5. doi: 10.1007/BF00915360.
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B cell function in acquired "common-variable" hypogammaglobulinemia: proliferative responses to lymphokines.获得性“常见变异型”低丙种球蛋白血症中的B细胞功能：对淋巴因子的增殖反应。
Clin Immunol Immunopathol. 1989 May;51(2):196-204. doi: 10.1016/0090-1229(89)90019-6.
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Classification of patients with common variable immunodeficiency by B cell secretion of IgM and IgG in response to anti-IgM and interleukin-2.通过B细胞分泌IgM和IgG对抗IgM和白细胞介素-2的反应对常见可变免疫缺陷患者进行分类。
Clin Immunol Immunopathol. 1990 Aug;56(2):239-48. doi: 10.1016/0090-1229(90)90145-g.
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Cellular abnormalities in common variable immunodeficiency.常见可变免疫缺陷中的细胞异常。
Immunodefic Rev. 1990;2(3):199-219.
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T and B cell defects in common variable immunodeficiency.常见可变免疫缺陷中的T细胞和B细胞缺陷
Immunol Invest. 1991 Apr;20(2):143-50. doi: 10.3109/08820139109050782.
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Lymphocyte surface phenotype in common variable immunodeficiency.普通可变免疫缺陷中的淋巴细胞表面表型
Dis Markers. 1992 Mar-Apr;10(2):67-80.
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