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[淋巴增生性疾病中的尿蛋白]

[Uroproteins in lymphoproliferative diseases].

作者信息

Pushkarev I

出版信息

Haematologia (Budap). 1976;10(2):221-30.

PMID:828897
Abstract

Uroproteins were studied in 86 cases of chronic lymphatic leukaemia, 28 of chronic lymphoreticulosis and 24 of Hodgkin disease, using polyacrylamide gel disk-electrophoresis. Proteinuria was found in 63 to 79% of the patients in all three groups. The amount of protein rarely exceeded 0.1g/litre. Disproteinuria was observed in the majority of patients. Urinary components which were present in 36% of cases with chronic lympholeucosis and in 25% of them with chronic lymphoreticulosis were identified as immunoglobulin light chains; the kappa type predominated. Of the 24 cases of Hodgkin disease, urinary M components were found in two patients only.

摘要

采用聚丙烯酰胺凝胶圆盘电泳法,对86例慢性淋巴细胞白血病、28例慢性淋巴组织增殖症和24例霍奇金病患者的尿蛋白进行了研究。在所有三组患者中,63%至79%的患者出现蛋白尿。蛋白量很少超过0.1克/升。大多数患者观察到蛋白尿异常。在36%的慢性淋巴细胞白血病患者和25%的慢性淋巴组织增殖症患者的尿液成分中,鉴定出免疫球蛋白轻链;以κ型为主。在24例霍奇金病患者中,仅在两名患者中发现尿M成分。

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