Johnson B R, Remeikis N A
Department of Endodontics, College of Dentistry, University of Illinois, Chicago.
J Endod. 1993 Jan;19(1):40-3. doi: 10.1016/S0099-2399(06)81040-X.
Although the tissue solvent and bactericidal properties of sodium hypochlorite are well known, the effective shelf-life of prepared sodium hypochlorite solutions is not known. The stability of sodium hypochlorite is adversely affected by exposure to high temperature, light, air, and the presence of organic and inorganic contaminants. The purpose of this study was to investigate the variables of storage conditions and time on the tissue-dissolving capacity of three different concentrations of sodium hypochlorite. Fresh frozen human umbilical cord was used as the tissue sample for this experiment. Tissue samples were dissolved at time intervals ranging from 1 day to 10 wk in 5.25%, 2.62%, and 1.0% solutions of sodium hypochlorite. The tissue-dissolving ability of 5.25% sodium hypochlorite remains stable for at least 10 wk. The tissue-dissolving ability of 2.62% and 1.0% sodium hypochlorite remains relatively stable for 1 wk after mixing, then exhibits a significant decrease in tissue-dissolving ability at 2 wk and beyond.
尽管次氯酸钠的组织溶解和杀菌特性广为人知，但所制备的次氯酸钠溶液的有效保质期却并不清楚。次氯酸钠的稳定性会因暴露于高温、光照、空气以及有机和无机污染物的存在而受到不利影响。本研究的目的是调查储存条件和时间变量对三种不同浓度次氯酸钠组织溶解能力的影响。新鲜冷冻的人脐带被用作本实验的组织样本。组织样本在1天至10周的时间间隔内，分别置于5.25%、2.62%和1.0%的次氯酸钠溶液中进行溶解。5.25%次氯酸钠的组织溶解能力至少在10周内保持稳定。2.62%和1.0%次氯酸钠的组织溶解能力在混合后1周内相对稳定，然后在2周及以后组织溶解能力显著下降。
