Zweegman S, Sibinga L, Huijgens P C
Afd. Inwendige Geneeskunde, Academisch Ziekenhuis Vrije Universiteit, Amsterdam.
Ned Tijdschr Geneeskd. 1994 Jan 1;138(1):35-8.
Hepatosplenic candidiasis is increasingly observed in patients with a haematological malignancy who have received chemotherapy. A case history is described of a male aged 45 who developed symptoms of hepatosplenic candidiasis caused by Candida tropicalis after treatment for acute myeloid leukaemia. The disease is characterized by persistent fever after recovery of the leukopenia induced by the chemotherapy. Echographic and computer-tomographic examination may reveal abscess patterns specific of Candida in the liver. Treatment consists of amphotericin B intravenously or fluconazole orally. Protracted treatment is frequently required.
肝脾念珠菌病在接受化疗的血液系统恶性肿瘤患者中越来越常见。本文描述了一例45岁男性的病例，该患者在急性髓系白血病治疗后出现了由热带念珠菌引起的肝脾念珠菌病症状。该病的特征是化疗诱导的白细胞减少症恢复后持续发热。超声和计算机断层扫描检查可能会发现肝脏中念珠菌特有的脓肿模式。治疗包括静脉注射两性霉素B或口服氟康唑。通常需要长期治疗。
