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使用奥本宁干奶牛制剂治疗奶牛干奶期乳腺炎

[Treatment of mastitis during the dry period of cows using the preparation Orbenin-dry cow].

作者信息

Vyhnálek J, Skaloud J

出版信息

Vet Med (Praha). 1976 Dec;21(12):709-15.

PMID:828998
Abstract

The paper describes the study of the extent to which the use of the Orbenin -- dry cow preparation (with cloxacillin as the active substance) was successful in the treatment of mastitis caused by Streptococcus agalactiae. Effectiveness was evaluated on the basis of the bacteriological examination of the udder-quarter samples of milk obtained from the tested cows immediately before getting dry and after the resumption of lactation. The preparation was applied in a single dose at the beginning of the dry period at the rate of 500 mg cloxacillin per 1 udder quarter. In the first herd 11 cows were treated with a positive finding (str. agalactiae, penicillin-resistant) in 26 quarters. In two control examinations the causative agent was always detected in one quarter (not in the same), i. e. in 3.8% of the initial number. In the second herd the causative agent (sensitive to penicillin) was found in 67 quarters before treatment (the total number of cows tested being 25); after treatment it was found in two cows in one quarter in each case (3.0% of the initial number). In an informative testing of effectiveness, the Orbenin L. A. preparation, designed for lactating cows, was applied repeatedly (3 times with 48-hour intervals) to six cows with subclinical streptococcal mastitis (Str. agalactiae, penicillin-resistant, detected in 11 quarters). After treatment the causative agent was found only in one quarter during the second examination. The therapeutic effect can be considered very good; the form of the drug and the method of its application allow for prompt and easy application.

摘要

本文描述了使用奥苯宁干奶牛制剂(活性物质为氯唑西林)治疗无乳链球菌引起的乳腺炎的成功程度研究。根据在即将干奶前和恢复泌乳后从受试奶牛采集的乳房四分之一乳样的细菌学检查来评估有效性。在干奶期开始时,以每四分之一乳房500毫克氯唑西林的剂量单次施用该制剂。在第一个牛群中,对26个乳房四分之一进行治疗的11头奶牛检测呈阳性(无乳链球菌,耐青霉素)。在两次对照检查中,始终在一个乳房四分之一中检测到病原体(不是同一个),即占初始数量的3.8%。在第二个牛群中,治疗前在67个乳房四分之一中发现病原体(对青霉素敏感)(受试奶牛总数为25头);治疗后,在每例中分别在两头奶牛的一个乳房四分之一中发现病原体(占初始数量的3.0%)。在一项有效性信息测试中,将专为泌乳奶牛设计的奥苯宁长效制剂重复(间隔48小时3次)应用于6头患有亚临床链球菌性乳腺炎(无乳链球菌,耐青霉素,在11个乳房四分之一中检测到)的奶牛。治疗后,在第二次检查时仅在一个乳房四分之一中发现病原体。治疗效果可认为非常好;药物剂型及其施用方法便于快速简便地应用。

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