Netland P A, Walton D S
Department of Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston 02114.
Ophthalmic Surg. 1993 Nov;24(11):723-9.
To assess the use of drainage implants in pediatric patients with glaucoma refractory to conventional medical and surgical therapy, we retrospectively reviewed 20 consecutive eyes in children 10 years of age or younger treated with 16 Molteno (three of which were removed and replaced with second Molteno shunts) and seven Baerveldt implants. The age of the patients ranged from 1 month to 10 years (mean, 3 years). The patients had undergone a mean of two previous failed glaucoma procedures (range, one to six). The mean intraocular pressure (IOP) prior to drainage tube implantation was 37 +/- 4 mm Hg, compared with a mean of 18 +/- 6 mm Hg following surgery, with average postoperative follow up of 25 months (range, 8 to 41 months). The overall success, defined as IOP < or = 21 mm Hg without further surgical therapy, was 80%. Postoperative glaucoma medications were required in 75% of patients. There were 23 complications, one of which resulted in decreased visual acuity. These findings demonstrate that drainage tube implants can be effective in lowering IOP in uncontrolled pediatric glaucomas. Patients often require postoperative glaucoma medications and close monitoring for complications.
为评估引流植入物在常规药物和手术治疗无效的小儿青光眼患者中的应用,我们回顾性分析了连续20例10岁及以下儿童患者的20只眼睛,这些患者接受了16例莫尔滕诺手术(其中3例移除后更换为第二个莫尔滕诺分流管)和7例贝尔维尔德特植入物手术。患者年龄从1个月至10岁(平均3岁)。患者此前平均经历了两次青光眼手术失败(范围为1至6次)。引流管植入术前平均眼压(IOP)为37±4 mmHg,术后平均为18±6 mmHg,术后平均随访25个月(范围为8至41个月)。总体成功率(定义为无需进一步手术治疗且眼压≤21 mmHg)为80%。75%的患者术后需要使用青光眼药物。共有23例并发症,其中1例导致视力下降。这些结果表明,引流管植入物可有效降低难治性小儿青光眼的眼压。患者术后常需使用青光眼药物并密切监测并发症。