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[恒河猴下丘脑含儿茶酚胺神经末梢的分布]

[Distribution of catecholamine containing nerve endings in the hypothalamus of the rhesus monkey].

作者信息

Ishikawa M, Shimada S, Handa H, Tanaka C

出版信息

No To Shinkei. 1976 Nov;28(11):1235-42.

PMID:829027
Abstract

Using the Falck-Hillarp method, the distribution of catecholamine nerve terminals in the rhesus monkey hypothalamus was studied. The distribution pattern was fundamentally similar to that in the rat, cat and human fetus; abundunt catecholamine varicosities (presumed noradrenaline nerve terminals) were observed in the dorsomedial nucleus, supraoptic nucleus, paraventricular nucleus, medial forebrain bundle, periventricular layer and internal layer of the infundibulum, while little were in the mamillary nucleus, ventromedial nucleus and anterior hypothalamic area. A band of diffuse green fluorescence (dopamine nerve terminals) was observed around the capillary loops in the external layer of the infundibulum. the discrepancy with the rat was noted in the abundunt noradrenaline nerve terminals in the suprachiasmatic nucleus and denser innervation of them in the arcuate nucleus and internal layer of the infundibulum. In addition to the noradrenaline nerve fibers from the peripheral sympathetic NA nerve, the noradrenaline nerve terminals of central origin closely approximated to the small intracerebral vessels.

摘要

采用福尔克-希拉尔普方法,研究了恒河猴下丘脑儿茶酚胺神经末梢的分布。其分布模式与大鼠、猫和人类胎儿基本相似;在背内侧核、视上核、室旁核、内侧前脑束、室周层和漏斗内层观察到大量儿茶酚胺曲张体(推测为去甲肾上腺素神经末梢),而在乳头体核、腹内侧核和下丘脑前区则很少。在漏斗外层的毛细血管袢周围观察到一条弥漫性绿色荧光带(多巴胺神经末梢)。在视交叉上核中丰富的去甲肾上腺素神经末梢以及它们在弓状核和漏斗内层更密集的神经支配方面,与大鼠存在差异。除了来自外周交感神经去甲肾上腺素能神经的去甲肾上腺素神经纤维外,中枢起源的去甲肾上腺素神经末梢紧密靠近脑内小血管。

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