Methotrexate in rheumatoid arthritis: can current knowledge and experience justify its use as a first-line disease-modifying agent?
作者信息
Tariq S, Tariq S M
机构信息
Department of Rheumatology, Hammersmith Hospital, London, UK.
出版信息
Postgrad Med J. 1993 Oct;69(816):775-80. doi: 10.1136/pgmj.69.816.775.
Abstract
摘要
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Therapeutic abortions with a folic acid antagonist, 4-aminopteroylglutamic acid (4-amino P.G.A) administered by the oral route.通过口服途径给予叶酸拮抗剂4-氨基蝶酰谷氨酸（4-氨基PGA）进行治疗性流产。
Am J Obstet Gynecol. 1952 Jun;63(6):1298-304. doi: 10.1016/s0002-9378(16)38924-4.
2
Therapeutic suppression of tissue reactivity. II. Effect of aminopterin in rheumatoid arthritis and psoriasis.组织反应性的治疗性抑制。II. 氨甲蝶呤对类风湿性关节炎和银屑病的作用。
Am J Med Sci. 1951 Feb;221(2):176-82.
3
Methotrexate guidelines--revised.
J Am Acad Dermatol. 1982 Feb;6(2):145-55. doi: 10.1016/s0190-9622(82)80064-9.
4
Frequency of malignant neoplasms in 248 long-term methotrexate-treated psoriatics. A preliminary study.248例长期接受甲氨蝶呤治疗的银屑病患者的恶性肿瘤发生率。一项初步研究。
Dermatologica. 1983;167(5):260-1. doi: 10.1159/000249793.
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Acute lung disease associated with low-dose pulse methotrexate therapy in patients with rheumatoid arthritis.类风湿关节炎患者低剂量脉冲甲氨蝶呤治疗相关的急性肺疾病
Arthritis Rheum. 1983 Oct;26(10):1269-74. doi: 10.1002/art.1780261015.
6
Accumulation of DNA strand breaks and methotrexate cytotoxicity.DNA链断裂的积累与甲氨蝶呤的细胞毒性。
Proc Natl Acad Sci U S A. 1984 Sep;81(18):5694-8. doi: 10.1073/pnas.81.18.5694.
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Sister chromatid exchange in patients treated with methotrexate for psoriasis.用甲氨蝶呤治疗银屑病患者的姐妹染色单体交换
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N Engl J Med. 1983 Mar 3;308(9):473-6. doi: 10.1056/NEJM198303033080901.
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Liver damage due to methotrexate in patients with psoriasis.银屑病患者中因甲氨蝶呤导致的肝损伤。
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