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Methotrexate in rheumatoid arthritis: can current knowledge and experience justify its use as a first-line disease-modifying agent?

作者信息

Tariq S, Tariq S M

机构信息

Department of Rheumatology, Hammersmith Hospital, London, UK.

出版信息

Postgrad Med J. 1993 Oct;69(816):775-80. doi: 10.1136/pgmj.69.816.775.

Abstract
摘要

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Methotrexate guidelines--revised.
J Am Acad Dermatol. 1982 Feb;6(2):145-55. doi: 10.1016/s0190-9622(82)80064-9.
6
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
Proc Natl Acad Sci U S A. 1984 Sep;81(18):5694-8. doi: 10.1073/pnas.81.18.5694.
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Sister chromatid exchange in patients treated with methotrexate for psoriasis.
J Invest Dermatol. 1984 May;82(5):458-9. doi: 10.1111/1523-1747.ep12260950.
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No increase in second tumors after cytotoxic chemotherapy for gestational trophoblastic tumors.
N Engl J Med. 1983 Mar 3;308(9):473-6. doi: 10.1056/NEJM198303033080901.
10
Liver damage due to methotrexate in patients with psoriasis.
Br Med J. 1971 Mar 20;1(5750):625-30. doi: 10.1136/bmj.1.5750.625.

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