Johnson J K
Department of Biochemistry, Dumfries & Galloway Royal Infirmary.
Scott Med J. 1993 Oct;38(5):142-4. doi: 10.1177/003693309303800505.
This is a report of an audit exercise that was designed to study the effectiveness of treating thyrotoxic patients with a standard dose--370 MBq--of radioactive iodine (131l). This treatment was received by 183 patients in one centre between 1977 and 1989. The results were assessed from the answers to 114 questionnaires that had been completed by the patients' general practitioners. The patients were aged between 28 and 85 years; 86% were female; 42% had been treated previously with anti-thyroid drugs. Ninety-five of the patients (83%) became euthyroid after a single dose of 131l; 18 required one further dose; and one required two further doses. At the time of the survey, 32 (28%) were euthyroid, while 82 patients (72%) had become hypothyroid and required treatment with thyroxine. Within five years of treatment, 85% of the patients had become hypothyroid. These results are compared with those from two other centres.
这是一份关于一项审核工作的报告，该审核旨在研究用标准剂量——370兆贝可——的放射性碘（131I）治疗甲状腺毒症患者的有效性。1977年至1989年间，一个中心的183名患者接受了这种治疗。结果是根据患者的全科医生填写的114份问卷的答案进行评估的。患者年龄在28岁至85岁之间；86%为女性；42%曾接受过抗甲状腺药物治疗。95名患者（83%）在单次服用131I后甲状腺功能恢复正常；18名患者需要再服用一剂；1名患者需要再服用两剂。在调查时，32名患者（28%）甲状腺功能正常，而82名患者（72%）出现甲状腺功能减退，需要用甲状腺素治疗。治疗后五年内，85%的患者出现甲状腺功能减退。这些结果与其他两个中心的结果进行了比较。
