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Alzheimer's disease and possible gene interaction.

作者信息

St George-Hyslop P, McLachlan D C, Tsuda T, Rogaev E, Karlinsky H, Lippa C F, Pollen D

出版信息

Science. 1994 Jan 28;263(5146):537. doi: 10.1126/science.8290965.

DOI:10.1126/science.8290965
PMID:8290965
Abstract
摘要

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Alzheimer's disease and possible gene interaction.
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Genetic Biomarkers on Age-Related Cognitive Decline.与年龄相关的认知衰退的基因生物标志物
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Optimizing the fragment complementation of APEX2 for detection of specific protein-protein interactions in live cells.优化 APEX2 的片段互补性,用于检测活细胞中特定的蛋白质-蛋白质相互作用。
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Panel of Genetic Variations as a Potential Non-invasive Biomarker for Early Diagnosis of Alzheimer's Disease.
基因变异面板作为阿尔茨海默病早期诊断的潜在非侵入性生物标志物。
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The genetics and neuropathology of Alzheimer's disease.阿尔茨海默病的遗传学和神经病理学。
Acta Neuropathol. 2012 Sep;124(3):305-23. doi: 10.1007/s00401-012-0996-2. Epub 2012 May 23.
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Genetic studies in Alzheimer's disease.阿尔茨海默病的遗传学研究。
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Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.荟萃分析证实CR1、CLU和PICALM为阿尔茨海默病风险基因座,并揭示了与APOE基因型的相互作用。
Arch Neurol. 2010 Dec;67(12):1473-84. doi: 10.1001/archneurol.2010.201. Epub 2010 Aug 9.
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