Ippolito V, Brien E W, Menendez L R, Mirra J M
Division of Orthopedic Oncology, Hospital of the Good Samaritan, Los Angeles, CA 90017.
Skeletal Radiol. 1993 Nov;22(8):604-8. doi: 10.1007/BF00197145.
We have presented the first case of a lipoma-like liposarcoma of the soft tissues with high-grade malignant transformation to a high-grade osteosarcoma, the latter component of which responded well to systemic chemotherapy. With 4 months of follow-up the patient is without evidence of disseminated disease. The various types of liposarcoma are listed and several described in some detail. Of particular importance is the potential for development of a highly malignant sarcoma from a relatively indolent low-grade liposarcoma, with even osteosarcoma developing.
我们报告了首例软组织脂肪瘤样脂肪肉瘤发生高级别恶性转化为高级别骨肉瘤的病例，后者对全身化疗反应良好。经过4个月的随访，患者无播散性疾病迹象。文中列出了各种类型的脂肪肉瘤，并对其中几种进行了详细描述。特别重要的是，相对惰性的低级别脂肪肉瘤有发展为高度恶性肉瘤的可能性，甚至会发展为骨肉瘤。
