Herz G
J Int Med Res. 1976;4(6):367-74. doi: 10.1177/030006057600400601.
The normal bacterial flora of the skin of 100 healthy children was studied in a paediatric practice with regard to the germ spectrum and the resistance constellation, by means of abrasion skin samples taken from the upper part of the back. Staphylococcus albus was by far the most predominant bacteria, followed by Sarcina bacteria and Corynebacteria. The high degree of pervasion of this physiological cutaneous flora with antibiotic-resistant strains increases the suspicion that in the case of florid bacterial skin infections in children, subsequent to traumatic or inflammatory changes of the integument, the antibiotic resistance of the normal resident flora can be transferred to the pathogenic flora. In view of the endemic resistance of pathogenic and saprobic strains of bacteria against practically all antibiotics at present used in paediatric practice, it is to be urgently recommended that instead of antibiotics topical braod-spectrum antimicrobial agents (antiseptics), e.g. clioquinol, triclosan, etc., should preferably be used.
在一家儿科诊所,通过从背部上方采集的皮肤擦屑样本,对100名健康儿童皮肤的正常细菌菌群进行了关于菌种谱和耐药情况的研究。白色葡萄球菌是迄今为止最主要的细菌,其次是八叠球菌和棒状杆菌。这种生理性皮肤菌群中耐药菌株的高度普遍性增加了一种怀疑,即在儿童出现明显的细菌性皮肤感染时,在皮肤发生创伤或炎症变化之后,正常常驻菌群的抗生素耐药性可能会转移到致病菌群。鉴于目前儿科实践中使用的几乎所有抗生素,致病和腐生菌株都存在地方性耐药情况,迫切建议优先使用外用广谱抗菌剂(防腐剂),如氯碘羟喹、三氯生等,而不是抗生素。