Costongs G M, Janson P C
Dept. Clinical Chemistry, Maaslandziekenhuis, Sittard, The Netherlands.
Eur J Clin Chem Clin Biochem. 1993 Oct;31(10):701-6. doi: 10.1515/cclm.1993.31.10.701.
Two random access immunoassay analysers, the ACS-180 (Ciba Corning) and the AIA-1200 (Tosoh Corp.) were compared with respect to performance and user-friendliness. Precision studies revealed an almost equal intra-assay variation coefficient, but day-to-day reproducibility was better on the AIA-1200. Recovery of dilution series of tumour markers was too high with the ACS-180. Both systems were free from carry-over effects, on account of the extra wash step in the ACS-180 (for thyrotropin, carcinoembryonic antigen and human chorionic gonadotropin) and the separate pipetting tip in the AIA-1200. Reagent stability is better in the AIA-1200 than in the ACS-180. The AIA-1200 is more user-friendly and produces a higher throughput than the ACS-180 in daily routine operation (92 results/hour vs. 78 results/hour).
对两款随机接入免疫分析仪器，即ACS - 180（西巴科宁公司）和AIA - 1200（东曹株式会社）的性能和用户友好性进行了比较。精密度研究表明，两台仪器的批内变异系数几乎相等，但AIA - 1200的日间重复性更好。使用ACS - 180时，肿瘤标志物稀释系列的回收率过高。由于ACS - 180（针对促甲状腺激素、癌胚抗原和人绒毛膜促性腺激素）有额外的洗涤步骤以及AIA - 1200有单独的移液器吸头，两个系统均无携带污染效应。AIA - 1200的试剂稳定性优于ACS - 180。在日常常规操作中，AIA - 1200比ACS - 180更便于用户使用，且通量更高（每小时92个检测结果对每小时78个检测结果）。
