Dousei T, Miyata M, Tanaka Y, Izukura M, Kawashima Y, Matsuda H
First Department of Surgery, Osaka University Medical School, Japan.
Surg Today. 1993;23(11):954-9. doi: 10.1007/BF00308969.
Gastric inhibitory polypeptide (GIP) secretion after distal gastrectomy was compared between patients with diabetes mellitus (DM-group) and patients with normal glucose tolerance (N-group). GIP secretion in the DM-group was significantly greater in the early postcibal response period, but less in the late postcibal response period after gastrectomy, the total secretion of GIP being less after gastrectomy than before in this group. In the N-group, both the early and total postcibal responses of GIP were greater after gastrectomy than before. Moreover, the early and total postcibal secretions of GIP after gastrectomy were less in the DM-group than in the N-group. These findings suggest that GIP secretion in diabetics becomes insufficient after gastrectomy.
对糖尿病患者（DM组）和糖耐量正常患者（N组）远端胃切除术后胃抑制性多肽（GIP）的分泌情况进行了比较。DM组在进食后早期反应期GIP分泌显著增加，但在胃切除术后进食后期反应期GIP分泌减少，该组胃切除术后GIP的总分泌量低于术前。在N组，胃切除术后GIP的早期和总进食后反应均高于术前。此外，DM组胃切除术后GIP的早期和总进食后分泌量低于N组。这些发现表明，糖尿病患者胃切除术后GIP分泌不足。
