Chábová V, Tesar V, Lachmanová J, Zima T
Interní Klinika I. LF UK, Praha.
Cas Lek Cesk. 1993 Dec 6;132(23):705-8.
Rhabdomyolysis is damage of the skeletal muscles due to different causes which leads to the release of the contents of muscle cells into the blood stream and conversely to the penetration of water and other substances into muscles via the damaged membrane. This initiates many processes which damage the organism: hypovolaemia, hypocalcaemia, hyperkalaemia, hyperuricaemia, disseminated intravascular coagulation, renal failure. Renal failure in particular is a frequent and very serious complication. However, when correct treatment is provided, it is usually reversible. The diagnosis and differential diagnosis is not difficult if the possible presence of rhabdomyolysis is considered. Therapy involves in particular supplementation of the vascular volume and forced diuresis.
横纹肌溶解症是由不同原因导致的骨骼肌损伤，它会使肌肉细胞内容物释放到血流中，反之，水和其他物质会通过受损的细胞膜进入肌肉。这引发了许多损害机体的过程：低血容量、低钙血症、高钾血症、高尿酸血症、弥散性血管内凝血、肾衰竭。尤其是肾衰竭是一种常见且非常严重的并发症。然而，如果给予正确的治疗，它通常是可逆的。如果考虑到可能存在横纹肌溶解症，诊断和鉴别诊断并不困难。治疗尤其包括补充血容量和强制利尿。
