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一项关于超声控制下经宫颈输卵管原核胚胎移植与四至八细胞胚胎宫内移植的随机研究。

A randomized study of transcervical intrafallopian transfer of pronucleate embryos controlled by ultrasound versus intrauterine transfer of four- to eight-cell embryos.

作者信息

Scholtes M C, Roozenburg B J, Verhoeff A, Zeilmaker G H

机构信息

Department of Obstetrics and Gynecology, Academic Hospital Dijkzigt, Erasmus University Rotterdam, The Netherlands.

出版信息

Fertil Steril. 1994 Jan;61(1):102-4. doi: 10.1016/s0015-0282(16)56460-7.

Abstract

OBJECTIVE

To establish the value of transcervical intrafallopian transfer of zygotes and the accuracy of fallopian cannulation.

DESIGN

A prospective randomized study, comparing ultrasonically controlled transcervical intrafallopian transfer of zygotes with intrauterine transfer of cleaved embryos.

SETTING

Department of IVF of the Rotterdam Academic Hospital.

PATIENTS

One hundred forty-five patients with patent tubes entered the IVF program.

MAIN OUTCOME MEASURE

Pregnancy rates in both groups and ultrasound (US) assessment during fallopian cannulation and ET.

RESULTS

Transvaginal cannulation of the tube appears not to be sufficiently accurate when performed without US guidance. Catheter damage occurred in many cases. The previously reported superior implantation rate after intrafallopian transfer in comparison with intrauterine transfer could not be confirmed.

CONCLUSIONS

Intrauterine transfer of cleaved embryos remains the method of choice in IVF.

摘要

目的

确定经宫颈输卵管内受精卵移植的价值以及输卵管插管的准确性。

设计

一项前瞻性随机研究,比较超声引导下经宫颈输卵管内受精卵移植与分裂期胚胎宫内移植。

地点

鹿特丹学术医院体外受精科。

患者

145例输卵管通畅的患者进入体外受精程序。

主要观察指标

两组的妊娠率以及输卵管插管和胚胎移植期间的超声(US)评估。

结果

在没有超声引导的情况下进行经阴道输卵管插管时,准确性似乎不够。许多病例出现导管损伤。先前报道的输卵管内移植后与宫内移植相比更高的着床率未能得到证实。

结论

分裂期胚胎宫内移植仍然是体外受精的首选方法。

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