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多胎妊娠减胎术效果改善:72例报告

Improved results in multifetal pregnancy reduction: a report of 72 cases.

作者信息

Lipitz S, Yaron Y, Shalev J, Achiron R, Zolti M, Mashiach S

机构信息

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Fertil Steril. 1994 Jan;61(1):59-61. doi: 10.1016/s0015-0282(16)56453-x.

DOI:10.1016/s0015-0282(16)56453-x
PMID:8293845
Abstract

OBJECTIVE

To evaluate pregnancy outcome after either transabdominal or transvaginal multifetal pregnancy reduction.

DESIGN

A study of 72 consecutive multifetal pregnancy reductions.

SETTING

Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center Tel Hashomer, Israel.

PATIENTS

Seventy-two patients with multifetal pregnancies: 2 twins, 27 triplets, 26 quadruplets, 10 quintuplets, 3 sextuplets, 1 septuplet, 2 nontuplets, and one pregnancy with 12 fetuses.

INTERVENTION

Multifetal pregnancy reduction was performed at 9 to 13 weeks' gestation by either transabdominal or transvaginal potassium chloride injection.

MAIN OUTCOME MEASURES

Early and late complications related to the procedure, outcome of pregnancy, and comparison of two periods.

RESULTS

Procedures performed between 1984 and 1989 (36 patients) were associated with a 33.3% pregnancy loss, whereas those performed between 1990 and 1992 (36 patients) were associated with no pregnancy loss. Of the 17 patients with quintuplets or more, 10 (59%) delivered live and healthy newborns. No difference was found when comparing the transabdominal and the transvaginal approaches.

CONCLUSIONS

Both transvaginal and transabdominal approaches are comparable. There is a remarkable decrease in pregnancy loss with experience.

摘要

目的

评估经腹或经阴道多胎妊娠减胎术后的妊娠结局。

设计

一项对72例连续多胎妊娠减胎术的研究。

地点

以色列特拉维夫哈绍默市海姆·谢巴医疗中心妇产科。

患者

72例多胎妊娠患者:2例双胎、27例三胎、26例四胎、10例五胎、3例六胎、1例七胎、2例九胎以及1例怀有12个胎儿的妊娠。

干预措施

在妊娠9至13周时经腹或经阴道注射氯化钾进行多胎妊娠减胎术。

主要观察指标

与手术相关的早期和晚期并发症、妊娠结局以及两个时期的比较。

结果

1984年至1989年期间进行手术的36例患者妊娠丢失率为33.3%,而1990年至1992年期间进行手术的36例患者无妊娠丢失。17例五胎及以上妊娠患者中,10例(59%)分娩出活产健康新生儿。经腹和经阴道两种手术方式比较未发现差异。

结论

经阴道和经腹两种手术方式效果相当。随着经验积累,妊娠丢失率显著降低。

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