Takagi A, Suyama T, Kida M, Matsuda M, Matsumoto H, Kojima K, Taniyama K, Miyoshi A
Department of Gastroenterology, Shiga Medical Center for Adult Disease, Moriyama.
Rinsho Byori. 1993 Dec;41(12):1333-7.
Detection of Helicobacter pylori (H. pylori) by ELISA was compared with that by the culture method in 115 patients with gastroduodenal diseases. Both the sensitivity and specificity were more than 85% for patients with histological gastritis with neutrophil infiltration. This indicated that the detection of H. pylori by ELISA is useful for the diagnosis of H. pylori-related gastritis. Although the sensitivity between the ELISA and culture method was 85%, the specificity was 58.8%. The false negative detection may have been caused by a sampling error during the endoscopic biopsy.
对115例胃十二指肠疾病患者采用酶联免疫吸附测定（ELISA）法和培养法检测幽门螺杆菌（H. pylori）。对于有中性粒细胞浸润的组织学胃炎患者，ELISA法的敏感性和特异性均超过85%。这表明ELISA法检测H. pylori对诊断幽门螺杆菌相关性胃炎有用。虽然ELISA法与培养法之间的敏感性为85%，但特异性为58.8%。假阴性检测可能是由内镜活检时的取样误差所致。
