Hashimoto H, Yonezawa T, Sakaki T, Tsunoda S
Department of Neurosurgery, Okanami General Hospital.
No Shinkei Geka. 1994 Jan;22(1):81-4.
We reported a multicentric glioma having three separate lesions in the cerebrum. A 75-year old man was hospitalized with progressive disorientation. Computed tomography demonstrated two lesions in the left temporal lobe and the right frontal lobe. Magnetic resonance image disclosed one more lesion in the right occipital lobe. 2-staged operative procedures were performed for the left temporal and the right frontal tumors. It was histologically proven that one was glioblastoma and the other was anaplastic astrocytoma. The patient subsequently underwent radiotherapy and chemotherapy. Most multicentric gliomas are diagnosed in autopsy. Therefore it should be stressed that diagnosis is best made by biopsy or surgery. We discussed what therapy we should use for this fatal disease.
我们报告了一例在大脑中有三个独立病灶的多中心胶质瘤。一名75岁男性因进行性定向障碍入院。计算机断层扫描显示左颞叶和右额叶有两个病灶。磁共振成像显示右枕叶还有一个病灶。对左颞叶和右额叶肿瘤进行了两阶段手术。组织学证实一个是胶质母细胞瘤,另一个是间变性星形细胞瘤。患者随后接受了放疗和化疗。大多数多中心胶质瘤是在尸检中诊断出来的。因此,应强调最好通过活检或手术进行诊断。我们讨论了对于这种致命疾病应采用何种治疗方法。