Krasnov V A, Potashova V A, Zyrianova T V, Naryshkina S L
Probl Tuberk. 1993(5):14-6.
Recurrent tuberculosis was treated in hospital in 86 patients, 82.7% of whom had destructive disease, while 84.0% disseminated the bacteria. Combined chemotherapy included 4 tuberculostatic drugs: 10% isoniazid (7 mg/kg iv drip), streptomycin (0.5 g intramuscularly), rifadin (0.6 g orally) and tisamid (25-30 mg/kg orally). The drugs were given twice a week under the intermittent regimen in combination with 10% isoniazid (7 mg/kg) and streptomycin (0.5 g) inhalations. During a mean hospital stay of 6.5 months disappearance of destruction and discontinuation of the bacilli dissemination were achieved in 91.1% and 93.9% of patients, respectively, suffering from infiltrative and disseminated tuberculosis.
86例复发性结核病患者在医院接受治疗,其中82.7%患有破坏性疾病,84.0%传播细菌。联合化疗包括4种抗结核药物:10%异烟肼(7mg/kg静脉滴注)、链霉素(0.5g肌肉注射)、利福平(0.6g口服)和替沙米(25 - 30mg/kg口服)。这些药物在间歇治疗方案下每周给药两次,并联合10%异烟肼(7mg/kg)和链霉素(0.5g)吸入治疗。在平均住院6.5个月期间,浸润性和播散性结核病患者中分别有91.1%的患者破坏灶消失,93.9%的患者细菌传播停止。