Sokolova G B, Koriakin V A, Khalbaeva I V, Elistratova N A, Ziia A V
Probl Tuberk. 1993(5):21-3.
310 patients with pulmonary tuberculosis disseminating bacteria received isoniazid, rifampicin, streptomycin (ethambutol) and pirazinamid in different regimens and dosage forms. The drugs were administered in sequence or simultaneously, in single or divided doses. The best time and number characteristics as regards the discharge negativation were obtained in pirazinamid administration at a single dose daily or each other day irrespective of other drugs intake. 100 patients were given isoniazid, rifampicin and pirazinamid in multicomponent form tricox (Jemis, India). Tricox proved effective under additional administration of isoniazid in the same dose as was fixed in tricox.
310例播散性肺结核患者接受了不同方案和剂型的异烟肼、利福平、链霉素（乙胺丁醇）和吡嗪酰胺治疗。这些药物按顺序或同时给药，采用单次或分次剂量。无论其他药物的服用情况如何，每日单次或隔日服用吡嗪酰胺时，在痰菌转阴方面获得了最佳的时间和次数特征。100例患者接受了多组分制剂tricox（印度Jemis公司生产）中的异烟肼、利福平及吡嗪酰胺治疗。在额外给予与tricox中固定剂量相同的异烟肼时，tricox被证明是有效的。
