Alunni-Bistocchi G, Orvietani P, Bittoun P, Ricci A, Lescot E
Istituto di Biochimica e Chimica Medica, Università degli Studi di Perugia, Italy.
Pharmazie. 1993 Nov;48(11):817-20.
The synthesis of 2,4-dimethyl-6 H-pyrido[3,2-b]carbazole (2a) and of its 9-methoxy (2b) and 9-hydroxy (2c) derivatives via the Combes-Beyer reaction is described. Pyridocarbazole 2a has been obtained by two different routes. In the course of the synthesis of 2b either a partial or a total demethoxylation has been observed depending on the route employed.
描述了通过Combes-Beyer反应合成2,4-二甲基-6H-吡啶并[3,2-b]咔唑(2a)及其9-甲氧基(2b)和9-羟基(2c)衍生物的方法。吡啶并咔唑2a已通过两种不同的路线获得。在2b的合成过程中,根据所采用的路线,观察到了部分或完全脱甲氧基化现象。