Tamburrini O, Della Sala M, Sessa M, Carallo O F, Imbimbo C, Mirone V, Morrone G
Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi di Reggio Calabria.
Radiol Med. 1993 Dec;86(6):851-5.
La Peyronie's disease (induratio penis plastica) is a degenerative process involving the penis, whose cause is still not fully explained. Adequate treatment requires the correct staging of La Peyronie's disease. Diagnostic imaging plays a major role after case history and clinics. Several imaging methods are used, including self-photography, plain radiography, CT, pharmaco-cavernosography, plain and duplex Doppler US. Enhanced MRI can be useful to correctly localize the plaques and to detect early changes in La Peyronie's disease, since the fibrous plaques with persistent inflammatory infiltration can be distinguished from the plaques in which inflammation has ceased. The diagnostic approach to La Peyronie's disease has been substantially modified by adding an examination during the erection induced by the intracavernosal injection of papaverine to the examination in the flaccid state. The authors report on the capabilities of unenhanced MRI after the intracavernosal injection of papaverine in steady chronic La Peyronie's disease. MRI was performed with an 0.5 T superconductive unit. Six patients (age range: 46-60 years, mean 52 years) who had been ill for about five years were studied. SE T1-weighted images and FS T2-weighted images were performed in both the flaccid and the erect states. Our results prove MR capabilities in both states in steady chronic La Peyronie's disease, which suggests MRI as the technique of choice for planning surgical treatment.
佩罗尼氏病(阴茎硬结症)是一种涉及阴茎的退行性病变过程,其病因仍未完全明确。充分的治疗需要对佩罗尼氏病进行正确分期。在病史和临床检查之后,诊断性影像学发挥着重要作用。人们使用了多种影像学方法,包括自拍、X线平片、CT、药物海绵体造影、普通及双功能多普勒超声。增强MRI有助于正确定位斑块并检测佩罗尼氏病的早期变化,因为可将伴有持续炎症浸润的纤维性斑块与炎症已消退的斑块区分开来。通过在阴茎海绵体内注射罂粟碱诱导勃起时进行检查并将其添加到疲软状态下的检查中,佩罗尼氏病的诊断方法已得到实质性改进。作者报告了在稳定的慢性佩罗尼氏病患者阴茎海绵体内注射罂粟碱后进行非增强MRI的能力。MRI检查使用0.5T超导装置。对6例患病约5年的患者(年龄范围:46 - 60岁,平均52岁)进行了研究。在疲软和勃起状态下均进行了SE T1加权成像和FS T2加权成像。我们的结果证明了在稳定的慢性佩罗尼氏病的两种状态下MRI的能力,这表明MRI是规划手术治疗的首选技术。