Fava M, Cruz F, Lastra M, Aguilar J, Loyola S
Departamento de Radiología, Hospital Clínico de la P Universidad Católica, Santiago de Chile.
Rev Med Chil. 1993 Jul;121(7):757-61.
The aim of this study was to assess the effectiveness and long term permeability of percutaneous biliary endoprostheses. Seventy three patients with biliary tract obstruction due to a primary malignant tumor (n = 60), lymph node metastases at the porta hepatis (n = 10) and benign stenosis of a biliary-enteric anastomosis (n = 3), were treated between 1985 and 1990. Plastic prostheses were installed in 63 patients and metallic in 10. The procedure had a 30% incidence of complications. Thirty three percent of the prostheses remained patent until patient's death. In 15 and 40% of patients, signs of prosthesis obstruction were observed three and six months after installation respectively, bearing in mind a mean survival of 24 weeks. In 90% of patients there was a clinical and laboratory improvement. Mortality was 30% at 30 days in the group of patients with malignant diseases. It is concluded that the installation of percutaneous biliary endoprostheses is a relatively safe and well tolerated procedure, with a low incidence of complications or mortality and that allows an effective biliary decompression.
本研究的目的是评估经皮胆道内支架的有效性和长期通畅性。1985年至1990年间,对73例因原发性恶性肿瘤导致胆道梗阻的患者(n = 60)、肝门淋巴结转移患者(n = 10)以及胆肠吻合口良性狭窄患者(n = 3)进行了治疗。63例患者安装了塑料支架,10例安装了金属支架。该手术并发症发生率为30%。33%的支架直至患者死亡时仍保持通畅。分别有15%和40%的患者在安装支架后3个月和6个月出现支架阻塞迹象,患者平均生存期为24周。90%的患者临床和实验室指标有所改善。恶性疾病患者组30天死亡率为30%。结论是,经皮胆道内支架置入术是一种相对安全且耐受性良好的手术,并发症或死亡率较低,能够实现有效的胆道减压。