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[药物源性迟发性运动障碍及其管理]

[Pharmacogenic tardive dyskinesias and their management].

作者信息

Böszörményi Z

出版信息

Psychiatr Neurol Med Psychol Beih. 1975;20-21:95-9.

PMID:829644
Abstract

The results can be related to three syndromes: the choreoathetotic, buccolingual and bucco-facio-mandibular. The author's results are compared with the most significant reviews in medical literature. With regard to the frequency in occurence of these retarded pharmacogenic dyskinesiae, incomparable and differing statements are found in separate authors. In the specific case-reports the quota of secondary or permanent dyskinesiae with chronic psychosics is less than 1/2%. However, the problem is gaining increasingly in importance, since more and more patients are being treated over a long period with neuroleptics. In two-thirds of the cases the disturbances which appeared were favourably influenced by Alpha-Mrthyl-Dopa.

摘要

这些结果可与三种综合征相关

舞蹈徐动症、颊舌综合征和颊面下颌综合征。作者的结果与医学文献中最重要的综述进行了比较。关于这些迟发性药物性运动障碍的发生率,不同作者有不可比且不同的说法。在具体的病例报告中,慢性精神病患者继发或永久性运动障碍的比例不到1/2%。然而,这个问题正变得越来越重要,因为越来越多的患者长期接受抗精神病药物治疗。在三分之二的病例中,出现的障碍受到α-甲基多巴的有利影响。

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